Successful Milk Oral Immunotherapy Promotes Generation of Casein-Specific CD137+ FOXP3+ Regulatory T Cells Detectable in Peripheral Blood

Successful Milk Oral Immunotherapy Promotes Generation of Casein-Specific CD137+ FOXP3+ Regulatory T Cells Detectable in Peripheral Blood

BackgroundOral immunotherapy (OIT) is an emerging treatment for cow’s milk protein (CMP) allergy in children. The mechanisms driving tolerance following OIT are not well understood. Regulatory T cells (TREG) cells are key inhibitors of allergic responses and promoters of allergen-specific tolerance....

Full description

Saved in:
Bibliographic Details
Main Authors: Yi Zhang, Lei Li, Geneviève Genest, Wei Zhao, Dan Ke, Sabrina Bartolucci, Nils Pavey, Tho-Alfakar Al-Aubodah, Duncan Lejtenyi, Bahar Torabi, Moshe Ben-Shoshan, Bruce Mazer, Ciriaco A. Piccirillo
Format: article
Language:EN
Published: Frontiers Media S.A. 2021
Subjects:
allergy
milk immunotherapy
regulatory T cells
clinical trial
tolerance
desensitization
Immunologic diseases. Allergy
RC581-607
Online Access:https://doaj.org/article/f9b863f16fe24acabcc832c2ecdfd742
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doaj.org/article/f9b863f16fe24acabcc832c2ecdfd742

Similar Items