Relation Between Tumor Budding and Endoscopic Classification, Degree of Malignancy in T1 Stage Esophageal Squamous Cell Carcinoma

Objective To investigate the clinical pathological significance of tumor budding in T1 stage esophageal squamous cell carcinoma. Methods Tumor budding was searched for in the resected tissues of T1 stage esophageal squamous cell carcinoma(ESCC), and the relation between tumor budding and endoscopic...

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Autores principales:	WANG Kang, YANG Chun
Formato:	article
Lenguaje:	ZH
Publicado:	Magazine House of Cancer Research on Prevention and Treatment 2021
Materias:	tumor budding esophageal squamous cell carcinoma endoscopic classification egfr Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
Acceso en línea:	https://doaj.org/article/f9b86b3b54034ca8bfd665266a4cebe5
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spelling	oai:doaj.org-article:f9b86b3b54034ca8bfd665266a4cebe52021-11-05T02:22:52ZRelation Between Tumor Budding and Endoscopic Classification, Degree of Malignancy in T1 Stage Esophageal Squamous Cell Carcinoma1000-857810.3971/j.issn.1000-8578.2021.21.0262https://doaj.org/article/f9b86b3b54034ca8bfd665266a4cebe52021-10-01T00:00:00Zhttp://html.rhhz.net/ZLFZYJ/html/8578.2021.21.0262.htmhttps://doaj.org/toc/1000-8578Objective To investigate the clinical pathological significance of tumor budding in T1 stage esophageal squamous cell carcinoma. Methods Tumor budding was searched for in the resected tissues of T1 stage esophageal squamous cell carcinoma(ESCC), and the relation between tumor budding and endoscopic classification, degree of malignancy in T1 ESCC were analyzed. Results The detection rate of tumor budding was significantly improved after EGFR labeling(P < 0.05). The detection rate of tumor budding in T1b ESCC was significantly higher than that of T1a SCC(P < 0.05). The detection rate of tumor budding in the cases with lymph node metastasis was significantly higher than that without lymph node metastasis(P < 0.05). The detection rate of tumor budding in stage ⅡB ESCC was significantly higher than those with stageⅠB(P < 0.05). Conclusion The detection rate of tumor budding in T1 ESCC is relatively high. The detection rates of tumor budding is improved by EGFR immunohistochemistrical labeling. The occurrence of tumor budding in T1 ESCC indicates more tumor aggression.WANG KangYANG ChunMagazine House of Cancer Research on Prevention and Treatmentarticletumor buddingesophageal squamous cell carcinomaendoscopic classificationegfrNeoplasms. Tumors. Oncology. Including cancer and carcinogensRC254-282ZHZhongliu Fangzhi Yanjiu, Vol 48, Iss 10, Pp 952-957 (2021)
institution	DOAJ
collection	DOAJ
language	ZH
topic	tumor budding esophageal squamous cell carcinoma endoscopic classification egfr Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
spellingShingle	tumor budding esophageal squamous cell carcinoma endoscopic classification egfr Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282 WANG Kang YANG Chun Relation Between Tumor Budding and Endoscopic Classification, Degree of Malignancy in T1 Stage Esophageal Squamous Cell Carcinoma
description	Objective To investigate the clinical pathological significance of tumor budding in T1 stage esophageal squamous cell carcinoma. Methods Tumor budding was searched for in the resected tissues of T1 stage esophageal squamous cell carcinoma(ESCC), and the relation between tumor budding and endoscopic classification, degree of malignancy in T1 ESCC were analyzed. Results The detection rate of tumor budding was significantly improved after EGFR labeling(P < 0.05). The detection rate of tumor budding in T1b ESCC was significantly higher than that of T1a SCC(P < 0.05). The detection rate of tumor budding in the cases with lymph node metastasis was significantly higher than that without lymph node metastasis(P < 0.05). The detection rate of tumor budding in stage ⅡB ESCC was significantly higher than those with stageⅠB(P < 0.05). Conclusion The detection rate of tumor budding in T1 ESCC is relatively high. The detection rates of tumor budding is improved by EGFR immunohistochemistrical labeling. The occurrence of tumor budding in T1 ESCC indicates more tumor aggression.
format	article
author	WANG Kang YANG Chun
author_facet	WANG Kang YANG Chun
author_sort	WANG Kang
title	Relation Between Tumor Budding and Endoscopic Classification, Degree of Malignancy in T1 Stage Esophageal Squamous Cell Carcinoma
title_short	Relation Between Tumor Budding and Endoscopic Classification, Degree of Malignancy in T1 Stage Esophageal Squamous Cell Carcinoma
title_full	Relation Between Tumor Budding and Endoscopic Classification, Degree of Malignancy in T1 Stage Esophageal Squamous Cell Carcinoma
title_fullStr	Relation Between Tumor Budding and Endoscopic Classification, Degree of Malignancy in T1 Stage Esophageal Squamous Cell Carcinoma
title_full_unstemmed	Relation Between Tumor Budding and Endoscopic Classification, Degree of Malignancy in T1 Stage Esophageal Squamous Cell Carcinoma
title_sort	relation between tumor budding and endoscopic classification, degree of malignancy in t1 stage esophageal squamous cell carcinoma
publisher	Magazine House of Cancer Research on Prevention and Treatment
publishDate	2021
url	https://doaj.org/article/f9b86b3b54034ca8bfd665266a4cebe5
work_keys_str_mv	AT wangkang relationbetweentumorbuddingandendoscopicclassificationdegreeofmalignancyint1stageesophagealsquamouscellcarcinoma AT yangchun relationbetweentumorbuddingandendoscopicclassificationdegreeofmalignancyint1stageesophagealsquamouscellcarcinoma
_version_	1718444567454285824

Relation Between Tumor Budding and Endoscopic Classification, Degree of Malignancy in T1 Stage Esophageal Squamous Cell Carcinoma

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