Low-dose rapamycin does not impair vascular integrity and tubular regeneration after kidney transplantation in rats

Abstract mTOR inhibitors offer advantages after kidney transplantation including antiviral and antitumor activity besides facilitating low calcineurin inhibitor exposure to reduce nephrotoxicity. Concerns about adverse effects due to antiproliferative and antiangiogenic properties have limited their...

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Autores principales: Uwe Hoff, Denise Markmann, Melina Nieminen-Kelhä, Klemens Budde, Björn Hegner
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/f9b8f0a4725d450481bd8e8e941ab87f
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