Tumor suppressor p53 regulates intestinal type 2 immunity
P53 is a well-known tumour suppressor, however its role in intestinal type 2 immunity is currently unclear. Here authors report that during parasitic infections, p53 triggers tuft cell Ca2+ influx and IL-25 release, and shows a regulatory role for p53 in intestinal type 2 immunity via transcriptiona...
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Autores principales: | Chun-Yuan Chang, Jianming Wang, Yuhan Zhao, Juan Liu, Xue Yang, Xuetian Yue, Huaying Wang, Fan Zhou, Juan M. Inclan-Rico, John J. Ponessa, Ping Xie, Lanjing Zhang, Mark C. Siracusa, Zhaohui Feng, Wenwei Hu |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/f9bfbce6c11f42c2bf999c334a0f4939 |
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