Age at Glaucoma Diagnosis in Germline Myocilin Mutation Patients: Associations with Polymorphisms in Protein Stabilities
Glaucoma is the leading cause of irreversible blindness worldwide, with elevated intraocular pressure (IOP) as the only known modifiable risk factor. Trabecular meshwork (TM)-inducible myocilin (the <i>MYOC</i> gene) was the first to be identified and linked to juvenile and primary open-...
Enregistré dans:
Auteurs principaux: | Tarin Tanji, Emily Cohen, Darrick Shen, Chi Zhang, Fei Yu, Anne L. Coleman, Jie J. Zheng |
---|---|
Format: | article |
Langue: | EN |
Publié: |
MDPI AG
2021
|
Sujets: | |
Accès en ligne: | https://doaj.org/article/f9c23b7aba584649b7d656841d16ca02 |
Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|
Documents similaires
-
Astragaloside IV Attenuates Ocular Hypertension in a Mouse Model of TGFβ2 Induced Primary Open Angle Glaucoma
par: Ramesh B. Kasetti, et autres
Publié: (2021) -
Cathepsin K Regulates Intraocular Pressure by Modulating Extracellular Matrix Remodeling and Actin-Bundling in the Trabecular Meshwork Outflow Pathway
par: Avinash Soundararajan, et autres
Publié: (2021) -
Switch to Autophagy the Key Mechanism for Trabecular Meshwork Death in Severe Glaucoma
par: Rao A, et autres
Publié: (2021) -
Preclinical Investigation of Goniotomy Using Four Different Techniques
par: Ammar DA, et autres
Publié: (2020) -
Combined Phacoemulsification and 360-Degree Endocyclophotocoagulation with and without a Kahook Dual Blade in Patients with Primary Open-Angle Glaucoma
par: Izquierdo JC, et autres
Publié: (2021)