A Controlled Human Infection Model of Group A <italic toggle="yes">Streptococcus</italic> Pharyngitis: Which Strain and Why?

A Controlled Human Infection Model of Group A <italic toggle="yes">Streptococcus</italic> Pharyngitis: Which Strain and Why?

ABSTRACT Group A Streptococcus (GAS) is a major cause of global infection-related morbidity and mortality. A modern controlled human infection model (CHIM) of GAS pharyngitis can accelerate vaccine development and pathogenesis research. A robust rationale for strain selection is central to meeting e...

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Main Authors: Joshua Osowicki, Kristy I. Azzopardi, Liam McIntyre, Tania Rivera-Hernandez, Cheryl-lynn Y. Ong, Ciara Baker, Christine M. Gillen, Mark J. Walker, Pierre R. Smeesters, Mark R. Davies, Andrew C. Steer
Format: article
Language:EN
Published: American Society for Microbiology 2019
Subjects:
Streptococcus pyogenes
controlled human infection model
group A Streptococcus
human challenge study
pharyngitis
vaccines
Microbiology
QR1-502
Online Access:https://doaj.org/article/f9d2f88500d34fb29810c3141be9b1b6
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https://doaj.org/article/f9d2f88500d34fb29810c3141be9b1b6

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