Amorphous silica nanoparticles trigger vascular endothelial cell injury through apoptosis and autophagy via reactive oxygen species-mediated MAPK/Bcl-2 and PI3K/Akt/mTOR signaling

Amorphous silica nanoparticles trigger vascular endothelial cell injury through apoptosis and autophagy via reactive oxygen species-mediated MAPK/Bcl-2 and PI3K/Akt/mTOR signaling

Caixia Guo,1,2 Man Yang,2,3 Li Jing,2,3 Ji Wang,2,3 Yang Yu,2,3 Yang Li,2,3 Junchao Duan,2,3 Xianqing Zhou,2,3 Yanbo Li,2,3 Zhiwei Sun2,3 1Department of Occupational and Environmental Health, School of Public Health, 2Beijing Key Laboratory of Environmental Toxicology, 3Department of Toxicology and...

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Autores principales: Guo C, Yang M, Jing L, Wang J, Yu Y, Li Y, Duan J, Zhou X, Sun Z
Formato: article
Lenguaje:EN
Publicado: Dove Medical Press 2016
Materias:
silica nanoparticle
endothelium
oxidative stress
N-acetylcysteine
apoptosis
autophagy
Medicine (General)
R5-920
Acceso en línea:https://doaj.org/article/f9de071e828a438884e08353c0c01863
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