A susceptibility locus in the IL12B but not LILRA3 region is associated with vascular damage in Takayasu arteritis

A susceptibility locus in the IL12B but not LILRA3 region is associated with vascular damage in Takayasu arteritis

Abstract HLA-B*52 is an established genetic factor in Takayasu arteritis (TAK). Recently, single nucleotide polymorphisms (SNPs) in IL12B (rs6871626) and LILRA3 (rs103294) were newly identified as non-HLA susceptibility loci in TAK. Here, we examined how these SNPs contribute to clinical characteris...

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Auteurs principaux: Keiichiro Kadoba, Ryu Watanabe, Takeshi Iwasaki, Toshiki Nakajima, Koji Kitagori, Shuji Akizuki, Kosaku Murakami, Ran Nakashima, Motomu Hashimoto, Masao Tanaka, Koichiro Ohmura, Akio Morinobu, Chikashi Terao, Hajime Yoshifuji
Format: article
Langue:EN
Publié: Nature Portfolio 2021
Sujets:
Medicine
R
Science
Q
Accès en ligne:https://doaj.org/article/f9e1ab64075742b083494f7b8b797a97
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https://doaj.org/article/f9e1ab64075742b083494f7b8b797a97

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