Regulatory protein HilD stimulates Salmonella Typhimurium invasiveness by promoting smooth swimming via the methyl-accepting chemotaxis protein McpC

Regulatory protein HilD stimulates Salmonella Typhimurium invasiveness by promoting smooth swimming via the methyl-accepting chemotaxis protein McpC

Protein HilD of Salmonella Typhimurium coordinates motility and host cell invasion by upregulating flagellar genes and a secretion system. Here, Cooper et al. show that HilD also modulates swimming behaviour by upregulating a subunit of the chemotactic receptor array, and this is important for invas...

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Bibliographic Details
Main Authors: Kendal G. Cooper, Audrey Chong, Laszlo Kari, Brendan Jeffrey, Tregei Starr, Craig Martens, Molly McClurg, Victoria R. Posada, Richard C. Laughlin, Canaan Whitfield-Cargile, L. Garry Adams, Laura K. Bryan, Sara V. Little, Mary Krath, Sara D. Lawhon, Olivia Steele-Mortimer
Format: article
Language:EN
Published: Nature Portfolio 2021
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Science
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Online Access:https://doaj.org/article/f9eb9852ba4b4ca3b6e9c4fcba33f955
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Summary:Protein HilD of Salmonella Typhimurium coordinates motility and host cell invasion by upregulating flagellar genes and a secretion system. Here, Cooper et al. show that HilD also modulates swimming behaviour by upregulating a subunit of the chemotactic receptor array, and this is important for invasion of epithelial cells.

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