Regulatory protein HilD stimulates Salmonella Typhimurium invasiveness by promoting smooth swimming via the methyl-accepting chemotaxis protein McpC

Protein HilD of Salmonella Typhimurium coordinates motility and host cell invasion by upregulating flagellar genes and a secretion system. Here, Cooper et al. show that HilD also modulates swimming behaviour by upregulating a subunit of the chemotactic receptor array, and this is important for invas...

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Autores principales: Kendal G. Cooper, Audrey Chong, Laszlo Kari, Brendan Jeffrey, Tregei Starr, Craig Martens, Molly McClurg, Victoria R. Posada, Richard C. Laughlin, Canaan Whitfield-Cargile, L. Garry Adams, Laura K. Bryan, Sara V. Little, Mary Krath, Sara D. Lawhon, Olivia Steele-Mortimer
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Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/f9eb9852ba4b4ca3b6e9c4fcba33f955
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spelling oai:doaj.org-article:f9eb9852ba4b4ca3b6e9c4fcba33f9552021-12-02T14:01:14ZRegulatory protein HilD stimulates Salmonella Typhimurium invasiveness by promoting smooth swimming via the methyl-accepting chemotaxis protein McpC10.1038/s41467-020-20558-62041-1723https://doaj.org/article/f9eb9852ba4b4ca3b6e9c4fcba33f9552021-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-20558-6https://doaj.org/toc/2041-1723Protein HilD of Salmonella Typhimurium coordinates motility and host cell invasion by upregulating flagellar genes and a secretion system. Here, Cooper et al. show that HilD also modulates swimming behaviour by upregulating a subunit of the chemotactic receptor array, and this is important for invasion of epithelial cells.Kendal G. CooperAudrey ChongLaszlo KariBrendan JeffreyTregei StarrCraig MartensMolly McClurgVictoria R. PosadaRichard C. LaughlinCanaan Whitfield-CargileL. Garry AdamsLaura K. BryanSara V. LittleMary KrathSara D. LawhonOlivia Steele-MortimerNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Kendal G. Cooper
Audrey Chong
Laszlo Kari
Brendan Jeffrey
Tregei Starr
Craig Martens
Molly McClurg
Victoria R. Posada
Richard C. Laughlin
Canaan Whitfield-Cargile
L. Garry Adams
Laura K. Bryan
Sara V. Little
Mary Krath
Sara D. Lawhon
Olivia Steele-Mortimer
Regulatory protein HilD stimulates Salmonella Typhimurium invasiveness by promoting smooth swimming via the methyl-accepting chemotaxis protein McpC
description Protein HilD of Salmonella Typhimurium coordinates motility and host cell invasion by upregulating flagellar genes and a secretion system. Here, Cooper et al. show that HilD also modulates swimming behaviour by upregulating a subunit of the chemotactic receptor array, and this is important for invasion of epithelial cells.
format article
author Kendal G. Cooper
Audrey Chong
Laszlo Kari
Brendan Jeffrey
Tregei Starr
Craig Martens
Molly McClurg
Victoria R. Posada
Richard C. Laughlin
Canaan Whitfield-Cargile
L. Garry Adams
Laura K. Bryan
Sara V. Little
Mary Krath
Sara D. Lawhon
Olivia Steele-Mortimer
author_facet Kendal G. Cooper
Audrey Chong
Laszlo Kari
Brendan Jeffrey
Tregei Starr
Craig Martens
Molly McClurg
Victoria R. Posada
Richard C. Laughlin
Canaan Whitfield-Cargile
L. Garry Adams
Laura K. Bryan
Sara V. Little
Mary Krath
Sara D. Lawhon
Olivia Steele-Mortimer
author_sort Kendal G. Cooper
title Regulatory protein HilD stimulates Salmonella Typhimurium invasiveness by promoting smooth swimming via the methyl-accepting chemotaxis protein McpC
title_short Regulatory protein HilD stimulates Salmonella Typhimurium invasiveness by promoting smooth swimming via the methyl-accepting chemotaxis protein McpC
title_full Regulatory protein HilD stimulates Salmonella Typhimurium invasiveness by promoting smooth swimming via the methyl-accepting chemotaxis protein McpC
title_fullStr Regulatory protein HilD stimulates Salmonella Typhimurium invasiveness by promoting smooth swimming via the methyl-accepting chemotaxis protein McpC
title_full_unstemmed Regulatory protein HilD stimulates Salmonella Typhimurium invasiveness by promoting smooth swimming via the methyl-accepting chemotaxis protein McpC
title_sort regulatory protein hild stimulates salmonella typhimurium invasiveness by promoting smooth swimming via the methyl-accepting chemotaxis protein mcpc
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/f9eb9852ba4b4ca3b6e9c4fcba33f955
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