CD36 maintains the gastric mucosa and associates with gastric disease

Jacome-Sosa et al. examine gastric function of CD36, reporting that CD36 knockout mice have altered gland organization and exhibit more fibronectin and inflammatory signaling. The authors find mucosal repair is abrogated due to defective epithelial cell renewal and progenitor cell differentiation, d...

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Autores principales:	Miriam Jacome-Sosa, Zhi-Feng Miao, Vivek S. Peche, Edward F. Morris, Ramkumar Narendran, Kathryn M. Pietka, Dmitri Samovski, Hei-Yong G. Lo, Terri Pietka, Andrea Varro, Latisha Love-Gregory, James R. Goldenring, Ondrej Kuda, Eric R. Gamazon, Jason C. Mills, Nada A. Abumrad
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/f9ec101e1f814b5fab8d34541185e8f0
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

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spelling	oai:doaj.org-article:f9ec101e1f814b5fab8d34541185e8f02021-11-07T12:19:55ZCD36 maintains the gastric mucosa and associates with gastric disease10.1038/s42003-021-02765-z2399-3642https://doaj.org/article/f9ec101e1f814b5fab8d34541185e8f02021-11-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-02765-zhttps://doaj.org/toc/2399-3642Jacome-Sosa et al. examine gastric function of CD36, reporting that CD36 knockout mice have altered gland organization and exhibit more fibronectin and inflammatory signaling. The authors find mucosal repair is abrogated due to defective epithelial cell renewal and progenitor cell differentiation, due to reduced fatty acid delivery and altered lipid metabolism, and find associations between low CD36 expression and gastric diseases.Miriam Jacome-SosaZhi-Feng MiaoVivek S. PecheEdward F. MorrisRamkumar NarendranKathryn M. PietkaDmitri SamovskiHei-Yong G. LoTerri PietkaAndrea VarroLatisha Love-GregoryJames R. GoldenringOndrej KudaEric R. GamazonJason C. MillsNada A. AbumradNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-15 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Biology (General) QH301-705.5
spellingShingle	Biology (General) QH301-705.5 Miriam Jacome-Sosa Zhi-Feng Miao Vivek S. Peche Edward F. Morris Ramkumar Narendran Kathryn M. Pietka Dmitri Samovski Hei-Yong G. Lo Terri Pietka Andrea Varro Latisha Love-Gregory James R. Goldenring Ondrej Kuda Eric R. Gamazon Jason C. Mills Nada A. Abumrad CD36 maintains the gastric mucosa and associates with gastric disease
description	Jacome-Sosa et al. examine gastric function of CD36, reporting that CD36 knockout mice have altered gland organization and exhibit more fibronectin and inflammatory signaling. The authors find mucosal repair is abrogated due to defective epithelial cell renewal and progenitor cell differentiation, due to reduced fatty acid delivery and altered lipid metabolism, and find associations between low CD36 expression and gastric diseases.
format	article
author	Miriam Jacome-Sosa Zhi-Feng Miao Vivek S. Peche Edward F. Morris Ramkumar Narendran Kathryn M. Pietka Dmitri Samovski Hei-Yong G. Lo Terri Pietka Andrea Varro Latisha Love-Gregory James R. Goldenring Ondrej Kuda Eric R. Gamazon Jason C. Mills Nada A. Abumrad
author_facet	Miriam Jacome-Sosa Zhi-Feng Miao Vivek S. Peche Edward F. Morris Ramkumar Narendran Kathryn M. Pietka Dmitri Samovski Hei-Yong G. Lo Terri Pietka Andrea Varro Latisha Love-Gregory James R. Goldenring Ondrej Kuda Eric R. Gamazon Jason C. Mills Nada A. Abumrad
author_sort	Miriam Jacome-Sosa
title	CD36 maintains the gastric mucosa and associates with gastric disease
title_short	CD36 maintains the gastric mucosa and associates with gastric disease
title_full	CD36 maintains the gastric mucosa and associates with gastric disease
title_fullStr	CD36 maintains the gastric mucosa and associates with gastric disease
title_full_unstemmed	CD36 maintains the gastric mucosa and associates with gastric disease
title_sort	cd36 maintains the gastric mucosa and associates with gastric disease
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/f9ec101e1f814b5fab8d34541185e8f0
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CD36 maintains the gastric mucosa and associates with gastric disease

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