Structural and biochemical insights into small RNA 3′ end trimming by Arabidopsis SDN1

Small RNA degrading nucleases (SDNs) can degrade short RNAs. Here the authors report the crystal structure of Arabidopsis SDN1 in complex with a single-stranded RNA, and provide new insight into 3′ end trimming mechanism of 3′ to 5′ riboexonucleases in the metabolism of various species of small RNAs...

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Autores principales:	Jiayi Chen, Li Liu, Chenjiang You, Jiaqi Gu, Wenjie Ruan, Lu Zhang, Jianhua Gan, Chunyang Cao, Ying Huang, Xuemei Chen, Jinbiao Ma
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/f9ee088e7f554180a52f530ae6775ba1
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spelling	oai:doaj.org-article:f9ee088e7f554180a52f530ae6775ba12021-12-02T16:49:23ZStructural and biochemical insights into small RNA 3′ end trimming by Arabidopsis SDN110.1038/s41467-018-05942-72041-1723https://doaj.org/article/f9ee088e7f554180a52f530ae6775ba12018-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-05942-7https://doaj.org/toc/2041-1723Small RNA degrading nucleases (SDNs) can degrade short RNAs. Here the authors report the crystal structure of Arabidopsis SDN1 in complex with a single-stranded RNA, and provide new insight into 3′ end trimming mechanism of 3′ to 5′ riboexonucleases in the metabolism of various species of small RNAs.Jiayi ChenLi LiuChenjiang YouJiaqi GuWenjie RuanLu ZhangJianhua GanChunyang CaoYing HuangXuemei ChenJinbiao MaNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Jiayi Chen Li Liu Chenjiang You Jiaqi Gu Wenjie Ruan Lu Zhang Jianhua Gan Chunyang Cao Ying Huang Xuemei Chen Jinbiao Ma Structural and biochemical insights into small RNA 3′ end trimming by Arabidopsis SDN1
description	Small RNA degrading nucleases (SDNs) can degrade short RNAs. Here the authors report the crystal structure of Arabidopsis SDN1 in complex with a single-stranded RNA, and provide new insight into 3′ end trimming mechanism of 3′ to 5′ riboexonucleases in the metabolism of various species of small RNAs.
format	article
author	Jiayi Chen Li Liu Chenjiang You Jiaqi Gu Wenjie Ruan Lu Zhang Jianhua Gan Chunyang Cao Ying Huang Xuemei Chen Jinbiao Ma
author_facet	Jiayi Chen Li Liu Chenjiang You Jiaqi Gu Wenjie Ruan Lu Zhang Jianhua Gan Chunyang Cao Ying Huang Xuemei Chen Jinbiao Ma
author_sort	Jiayi Chen
title	Structural and biochemical insights into small RNA 3′ end trimming by Arabidopsis SDN1
title_short	Structural and biochemical insights into small RNA 3′ end trimming by Arabidopsis SDN1
title_full	Structural and biochemical insights into small RNA 3′ end trimming by Arabidopsis SDN1
title_fullStr	Structural and biochemical insights into small RNA 3′ end trimming by Arabidopsis SDN1
title_full_unstemmed	Structural and biochemical insights into small RNA 3′ end trimming by Arabidopsis SDN1
title_sort	structural and biochemical insights into small rna 3′ end trimming by arabidopsis sdn1
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/f9ee088e7f554180a52f530ae6775ba1
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Structural and biochemical insights into small RNA 3′ end trimming by Arabidopsis SDN1

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