Is Intracanal Cryotherapy Effective in Reducing Postoperative Endodontic Pain? An Updated Systematic Review and Meta-Analysis of Randomized Clinical Trials

This research aimed to assess the potency of intracanal cold therapy in diminishing postoperative endodontic pain. PubMed, Scopus, the Cochrane Library, EMBASE, the Web of Science, grey literature, and endodontic journals were used to identify randomized controlled clinical trials evaluating postope...

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Autores principales:	Amal Almohaimede, Ebtissam Al-Madi
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	cold therapy cryotherapy endodontic pain intracanal cryotherapy Medicine R
Acceso en línea:	https://doaj.org/article/f9f32f5b38df40848802a17db0f1e963
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spelling	oai:doaj.org-article:f9f32f5b38df40848802a17db0f1e9632021-11-25T17:48:05ZIs Intracanal Cryotherapy Effective in Reducing Postoperative Endodontic Pain? An Updated Systematic Review and Meta-Analysis of Randomized Clinical Trials10.3390/ijerph1822117501660-46011661-7827https://doaj.org/article/f9f32f5b38df40848802a17db0f1e9632021-11-01T00:00:00Zhttps://www.mdpi.com/1660-4601/18/22/11750https://doaj.org/toc/1661-7827https://doaj.org/toc/1660-4601This research aimed to assess the potency of intracanal cold therapy in diminishing postoperative endodontic pain. PubMed, Scopus, the Cochrane Library, EMBASE, the Web of Science, grey literature, and endodontic journals were used to identify randomized controlled clinical trials evaluating postoperative pain after a final irrigation with a cold irrigant (as an experimental group) and a room temperature irrigant (as a control group). The risk of bias was rated according to the Cochrane Collaboration’s tool and the Grading Recommendation Assessment, Development, and Evaluation (GRADE) system was used to estimate the evidence quality. For the meta-analysis, a random effects model was utilized. The qualitative analysis contained 16 studies and the quantitative analysis contained 9 studies. The experimental groups showed a reduction in postoperative pain at 6 h (mean difference (MD) = −1.11; <i>p</i> = 0.0004; I<sup>2</sup> = 72%; low quality evidence), 24 h (MD = −1.08; <i>p</i> = 0.003; I<sup>2</sup> = 92%; low quality evidence), 48 h (MD = −0.38; <i>p</i> = 0.04; I<sup>2</sup> = 81%; low quality evidence), and 72 h (MD = −0.69; <i>p</i> = 0.04; I<sup>2</sup> = 90%; low quality evidence). A higher quality of evidence from more clinical trials is needed.Amal AlmohaimedeEbtissam Al-MadiMDPI AGarticlecold therapycryotherapyendodontic painintracanal cryotherapyMedicineRENInternational Journal of Environmental Research and Public Health, Vol 18, Iss 11750, p 11750 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	cold therapy cryotherapy endodontic pain intracanal cryotherapy Medicine R
spellingShingle	cold therapy cryotherapy endodontic pain intracanal cryotherapy Medicine R Amal Almohaimede Ebtissam Al-Madi Is Intracanal Cryotherapy Effective in Reducing Postoperative Endodontic Pain? An Updated Systematic Review and Meta-Analysis of Randomized Clinical Trials
description	This research aimed to assess the potency of intracanal cold therapy in diminishing postoperative endodontic pain. PubMed, Scopus, the Cochrane Library, EMBASE, the Web of Science, grey literature, and endodontic journals were used to identify randomized controlled clinical trials evaluating postoperative pain after a final irrigation with a cold irrigant (as an experimental group) and a room temperature irrigant (as a control group). The risk of bias was rated according to the Cochrane Collaboration’s tool and the Grading Recommendation Assessment, Development, and Evaluation (GRADE) system was used to estimate the evidence quality. For the meta-analysis, a random effects model was utilized. The qualitative analysis contained 16 studies and the quantitative analysis contained 9 studies. The experimental groups showed a reduction in postoperative pain at 6 h (mean difference (MD) = −1.11; <i>p</i> = 0.0004; I<sup>2</sup> = 72%; low quality evidence), 24 h (MD = −1.08; <i>p</i> = 0.003; I<sup>2</sup> = 92%; low quality evidence), 48 h (MD = −0.38; <i>p</i> = 0.04; I<sup>2</sup> = 81%; low quality evidence), and 72 h (MD = −0.69; <i>p</i> = 0.04; I<sup>2</sup> = 90%; low quality evidence). A higher quality of evidence from more clinical trials is needed.
format	article
author	Amal Almohaimede Ebtissam Al-Madi
author_facet	Amal Almohaimede Ebtissam Al-Madi
author_sort	Amal Almohaimede
title	Is Intracanal Cryotherapy Effective in Reducing Postoperative Endodontic Pain? An Updated Systematic Review and Meta-Analysis of Randomized Clinical Trials
title_short	Is Intracanal Cryotherapy Effective in Reducing Postoperative Endodontic Pain? An Updated Systematic Review and Meta-Analysis of Randomized Clinical Trials
title_full	Is Intracanal Cryotherapy Effective in Reducing Postoperative Endodontic Pain? An Updated Systematic Review and Meta-Analysis of Randomized Clinical Trials
title_fullStr	Is Intracanal Cryotherapy Effective in Reducing Postoperative Endodontic Pain? An Updated Systematic Review and Meta-Analysis of Randomized Clinical Trials
title_full_unstemmed	Is Intracanal Cryotherapy Effective in Reducing Postoperative Endodontic Pain? An Updated Systematic Review and Meta-Analysis of Randomized Clinical Trials
title_sort	is intracanal cryotherapy effective in reducing postoperative endodontic pain? an updated systematic review and meta-analysis of randomized clinical trials
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/f9f32f5b38df40848802a17db0f1e963
work_keys_str_mv	AT amalalmohaimede isintracanalcryotherapyeffectiveinreducingpostoperativeendodonticpainanupdatedsystematicreviewandmetaanalysisofrandomizedclinicaltrials AT ebtissamalmadi isintracanalcryotherapyeffectiveinreducingpostoperativeendodonticpainanupdatedsystematicreviewandmetaanalysisofrandomizedclinicaltrials
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Is Intracanal Cryotherapy Effective in Reducing Postoperative Endodontic Pain? An Updated Systematic Review and Meta-Analysis of Randomized Clinical Trials

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