Aurora-B kinase pathway controls the lateral to end-on conversion of kinetochore-microtubule attachments in human cells

Human chromosomes are captured along microtubule walls and then tethered to microtubule-ends through a multi-step end-on conversion process. Here the authors show that Aurora-B regulates end-on conversion in human cells and establish a late role for Astrin-SKAP complex in the end-on conversion proce...

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Autores principales:	Roshan L. Shrestha, Duccio Conti, Naoka Tamura, Dominique Braun, Revathy A. Ramalingam, Konstanty Cieslinski, Jonas Ries, Viji M. Draviam
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/f9f5bd0b1aa64801bac6724611b10ea2
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spelling	oai:doaj.org-article:f9f5bd0b1aa64801bac6724611b10ea22021-12-02T13:24:23ZAurora-B kinase pathway controls the lateral to end-on conversion of kinetochore-microtubule attachments in human cells10.1038/s41467-017-00209-z2041-1723https://doaj.org/article/f9f5bd0b1aa64801bac6724611b10ea22017-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-00209-zhttps://doaj.org/toc/2041-1723Human chromosomes are captured along microtubule walls and then tethered to microtubule-ends through a multi-step end-on conversion process. Here the authors show that Aurora-B regulates end-on conversion in human cells and establish a late role for Astrin-SKAP complex in the end-on conversion process.Roshan L. ShresthaDuccio ContiNaoka TamuraDominique BraunRevathy A. RamalingamKonstanty CieslinskiJonas RiesViji M. DraviamNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Roshan L. Shrestha Duccio Conti Naoka Tamura Dominique Braun Revathy A. Ramalingam Konstanty Cieslinski Jonas Ries Viji M. Draviam Aurora-B kinase pathway controls the lateral to end-on conversion of kinetochore-microtubule attachments in human cells
description	Human chromosomes are captured along microtubule walls and then tethered to microtubule-ends through a multi-step end-on conversion process. Here the authors show that Aurora-B regulates end-on conversion in human cells and establish a late role for Astrin-SKAP complex in the end-on conversion process.
format	article
author	Roshan L. Shrestha Duccio Conti Naoka Tamura Dominique Braun Revathy A. Ramalingam Konstanty Cieslinski Jonas Ries Viji M. Draviam
author_facet	Roshan L. Shrestha Duccio Conti Naoka Tamura Dominique Braun Revathy A. Ramalingam Konstanty Cieslinski Jonas Ries Viji M. Draviam
author_sort	Roshan L. Shrestha
title	Aurora-B kinase pathway controls the lateral to end-on conversion of kinetochore-microtubule attachments in human cells
title_short	Aurora-B kinase pathway controls the lateral to end-on conversion of kinetochore-microtubule attachments in human cells
title_full	Aurora-B kinase pathway controls the lateral to end-on conversion of kinetochore-microtubule attachments in human cells
title_fullStr	Aurora-B kinase pathway controls the lateral to end-on conversion of kinetochore-microtubule attachments in human cells
title_full_unstemmed	Aurora-B kinase pathway controls the lateral to end-on conversion of kinetochore-microtubule attachments in human cells
title_sort	aurora-b kinase pathway controls the lateral to end-on conversion of kinetochore-microtubule attachments in human cells
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/f9f5bd0b1aa64801bac6724611b10ea2
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Aurora-B kinase pathway controls the lateral to end-on conversion of kinetochore-microtubule attachments in human cells

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