Aurora-B kinase pathway controls the lateral to end-on conversion of kinetochore-microtubule attachments in human cells
Human chromosomes are captured along microtubule walls and then tethered to microtubule-ends through a multi-step end-on conversion process. Here the authors show that Aurora-B regulates end-on conversion in human cells and establish a late role for Astrin-SKAP complex in the end-on conversion proce...
Enregistré dans:
Auteurs principaux: | Roshan L. Shrestha, Duccio Conti, Naoka Tamura, Dominique Braun, Revathy A. Ramalingam, Konstanty Cieslinski, Jonas Ries, Viji M. Draviam |
---|---|
Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2017
|
Sujets: | |
Accès en ligne: | https://doaj.org/article/f9f5bd0b1aa64801bac6724611b10ea2 |
Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|
Documents similaires
-
Counteraction between Astrin-PP1 and Cyclin-B-CDK1 pathways protects chromosome-microtubule attachments independent of biorientation
par: Xinhong Song, et autres
Publié: (2021) -
Complete microtubule–kinetochore occupancy favours the segregation of merotelic attachments
par: Damian Dudka, et autres
Publié: (2018) -
Roles for the conserved spc105p/kre28p complex in kinetochore-microtubule binding and the spindle assembly checkpoint.
par: Cinzia Pagliuca, et autres
Publié: (2009) -
Author Correction: Lateral attachment of kinetochores to microtubules is enriched in prometaphase rosette and facilitates chromosome alignment and bi-orientation establishment
par: Go Itoh, et autres
Publié: (2018) -
The binding of Borealin to microtubules underlies a tension independent kinetochore-microtubule error correction pathway
par: Prasad Trivedi, et autres
Publié: (2019)