LprG-mediated surface expression of lipoarabinomannan is essential for virulence of Mycobacterium tuberculosis.

Mycobacterium tuberculosis employs various virulence strategies to subvert host immune responses in order to persist and cause disease. Interaction of M. tuberculosis with mannose receptor on macrophages via surface-exposed lipoarabinomannan (LAM) is believed to be critical for cell entry, inhibitio...

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Bibliographic Details
Main Authors: Rajiv L Gaur, Kangning Ren, Antje Blumenthal, Suresh Bhamidi, Fernando D González-Nilo, Mary Jackson, Richard N Zare, Sabine Ehrt, Joel D Ernst, Niaz Banaei
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2014
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Online Access:https://doaj.org/article/f9fc24d18cab44e6b9f1cabe82293ef1
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