Best strategies to recruit and enroll elderly Blacks into clinical and biomedical research

Lennox A Graham,1 Julius Ngwa,2 Oyonumo Ntekim,3 Oludolapo Ogunlana,4 Saba Wolday,4 Steven Johnson,3 Megan Johnson,4 Chimene Castor,3 Thomas V Fungwe,3 Thomas O Obisesan4 1Department of Health Management, College of Nursing and Allied Health Sciences, Howard University, Washington, DC, USA; 2Divisi...

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Autores principales:	Graham LA, Ngwa J, Ntekim O, Ogunlana O, Wolday S, Johnson S, Johnson M, Castor C, Fungwe TV, Obisesan TO
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2017
Materias:	Recruitment strategies Blacks Screening Community Outreach Clinical Trials Geriatrics RC952-954.6
Acceso en línea:	https://doaj.org/article/fa03f887dff04afba84120994777994d
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spelling	oai:doaj.org-article:fa03f887dff04afba84120994777994d2021-12-02T01:41:40ZBest strategies to recruit and enroll elderly Blacks into clinical and biomedical research1178-1998https://doaj.org/article/fa03f887dff04afba84120994777994d2017-12-01T00:00:00Zhttps://www.dovepress.com/best-strategies-to-recruit-and-enroll-elderly-blacks-into-clinical-and-peer-reviewed-article-CIAhttps://doaj.org/toc/1178-1998Lennox A Graham,1 Julius Ngwa,2 Oyonumo Ntekim,3 Oludolapo Ogunlana,4 Saba Wolday,4 Steven Johnson,3 Megan Johnson,4 Chimene Castor,3 Thomas V Fungwe,3 Thomas O Obisesan4 1Department of Health Management, College of Nursing and Allied Health Sciences, Howard University, Washington, DC, USA; 2Division of Cardiovascular Medicine, College of Medicine, Howard University, Washington, DC, USA; 3Department of Nutritional Sciences, College of Nursing and Allied Health Sciences, Howard University, Washington, DC, USA; 4Department of Internal Medicine, Howard University Teaching Hospital, Washington, DC, USA Background: Historically, Blacks have been disproportionately underrepresented in clinical trials. Outcomes associated with low Blacks’ participation in research include poor understanding of the predictors and treatment of the disease, increasing health disparities, poor health equity, and suboptimal wellness of the nation as a whole. To address this gap in research participation, we analyzed our recruitment data to identify the most effective strategies for enrolling older Blacks in clinical trials.Methods: Data used in these analyses were obtained from 3,266 potential volunteers, ages 50 or older, who completed a Mini-Mental State Exam as part of recruitment and screening for various clinical studies on Alzheimer’s disease. In order to determine the most effective strategies for engaging Blacks in clinical research, we used tests of proportion to assess significant differences in recruitment sources, counts, and percentages for optimal recruitment strategies by gender. Finally, we employed regression analyses to confirm our findings.Results: Of the total 3,266 screened, 2,830 Black volunteers were identified for further analysis. Overall, more women than men (73.8% vs 26.2%) participated in our recruitment activities. However, a significantly higher proportion of men than women were engaged through family (3.86% vs 1.30%, p=0.0004) and referral sources (5.89% vs 2.59%, p=0.0005). Compared to other sources for recruitment, we encountered a higher proportion of volunteers at health fairs (42.95%), and through advertisements (14.97%). In our sample, years of education and age did not appear to influence the likelihood of an encounter, screening, and potential participation.Conclusion: Our findings indicate Black men and women in our sample were predominantly recruited from health fairs and through advertisements tailored to their health needs and interests. Conversely, we mostly engaged Black men through family referrals and persons known to them, indicating a need for trust in their decision to engage study personnel and/or participate in clinical trials. Keywords: recruitment strategies, Blacks, screening, community outreach, clinical trialsGraham LANgwa JNtekim OOgunlana OWolday SJohnson SJohnson MCastor CFungwe TVObisesan TODove Medical PressarticleRecruitment strategiesBlacksScreeningCommunity OutreachClinical TrialsGeriatricsRC952-954.6ENClinical Interventions in Aging, Vol Volume 13, Pp 43-50 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Recruitment strategies Blacks Screening Community Outreach Clinical Trials Geriatrics RC952-954.6
spellingShingle	Recruitment strategies Blacks Screening Community Outreach Clinical Trials Geriatrics RC952-954.6 Graham LA Ngwa J Ntekim O Ogunlana O Wolday S Johnson S Johnson M Castor C Fungwe TV Obisesan TO Best strategies to recruit and enroll elderly Blacks into clinical and biomedical research
description	Lennox A Graham,1 Julius Ngwa,2 Oyonumo Ntekim,3 Oludolapo Ogunlana,4 Saba Wolday,4 Steven Johnson,3 Megan Johnson,4 Chimene Castor,3 Thomas V Fungwe,3 Thomas O Obisesan4 1Department of Health Management, College of Nursing and Allied Health Sciences, Howard University, Washington, DC, USA; 2Division of Cardiovascular Medicine, College of Medicine, Howard University, Washington, DC, USA; 3Department of Nutritional Sciences, College of Nursing and Allied Health Sciences, Howard University, Washington, DC, USA; 4Department of Internal Medicine, Howard University Teaching Hospital, Washington, DC, USA Background: Historically, Blacks have been disproportionately underrepresented in clinical trials. Outcomes associated with low Blacks’ participation in research include poor understanding of the predictors and treatment of the disease, increasing health disparities, poor health equity, and suboptimal wellness of the nation as a whole. To address this gap in research participation, we analyzed our recruitment data to identify the most effective strategies for enrolling older Blacks in clinical trials.Methods: Data used in these analyses were obtained from 3,266 potential volunteers, ages 50 or older, who completed a Mini-Mental State Exam as part of recruitment and screening for various clinical studies on Alzheimer’s disease. In order to determine the most effective strategies for engaging Blacks in clinical research, we used tests of proportion to assess significant differences in recruitment sources, counts, and percentages for optimal recruitment strategies by gender. Finally, we employed regression analyses to confirm our findings.Results: Of the total 3,266 screened, 2,830 Black volunteers were identified for further analysis. Overall, more women than men (73.8% vs 26.2%) participated in our recruitment activities. However, a significantly higher proportion of men than women were engaged through family (3.86% vs 1.30%, p=0.0004) and referral sources (5.89% vs 2.59%, p=0.0005). Compared to other sources for recruitment, we encountered a higher proportion of volunteers at health fairs (42.95%), and through advertisements (14.97%). In our sample, years of education and age did not appear to influence the likelihood of an encounter, screening, and potential participation.Conclusion: Our findings indicate Black men and women in our sample were predominantly recruited from health fairs and through advertisements tailored to their health needs and interests. Conversely, we mostly engaged Black men through family referrals and persons known to them, indicating a need for trust in their decision to engage study personnel and/or participate in clinical trials. Keywords: recruitment strategies, Blacks, screening, community outreach, clinical trials
format	article
author	Graham LA Ngwa J Ntekim O Ogunlana O Wolday S Johnson S Johnson M Castor C Fungwe TV Obisesan TO
author_facet	Graham LA Ngwa J Ntekim O Ogunlana O Wolday S Johnson S Johnson M Castor C Fungwe TV Obisesan TO
author_sort	Graham LA
title	Best strategies to recruit and enroll elderly Blacks into clinical and biomedical research
title_short	Best strategies to recruit and enroll elderly Blacks into clinical and biomedical research
title_full	Best strategies to recruit and enroll elderly Blacks into clinical and biomedical research
title_fullStr	Best strategies to recruit and enroll elderly Blacks into clinical and biomedical research
title_full_unstemmed	Best strategies to recruit and enroll elderly Blacks into clinical and biomedical research
title_sort	best strategies to recruit and enroll elderly blacks into clinical and biomedical research
publisher	Dove Medical Press
publishDate	2017
url	https://doaj.org/article/fa03f887dff04afba84120994777994d
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Best strategies to recruit and enroll elderly Blacks into clinical and biomedical research

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