Vascular endothelial growth factor in the fluid of the anterior chamber of the eye in patients with diabetic retinopathy, cataract andneovascular glaucoma

Aim. To study the role of vascular endothelial growth factor (VEGF-A) in the fluid of the anterior chamber of the eye (ACE) in the evolvement ofdiabetic retinopathy (DR) and the outcome of cataract surgery. Materials and methods. The study included 120 patients with diabetes mellitus (DM) operated...

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Autores principales:	Anatoliy Gennad'evich Kuz'min, Dmitriy Valentinovich Lipatov, Timofey Alexandrovich Chistyakov, Olga Mikhailovna Smirnova, Margarita Ivanovna Arbuzova, Alexander Viktorovich Il'in, Marina Vladimirovna Shestakova
Formato:	article
Lenguaje:	EN RU
Publicado:	Endocrinology Research Centre 2010
Materias:	vegf vascular endothelial growth factor (vegf-a) diabetic retinopathy cataract cataract surgery Nutritional diseases. Deficiency diseases RC620-627
Acceso en línea:	https://doaj.org/article/fa064ce190a048269adcb491be8b698c
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spelling	oai:doaj.org-article:fa064ce190a048269adcb491be8b698c2021-11-14T09:00:15ZVascular endothelial growth factor in the fluid of the anterior chamber of the eye in patients with diabetic retinopathy, cataract andneovascular glaucoma2072-03512072-037810.14341/2072-0351-5485https://doaj.org/article/fa064ce190a048269adcb491be8b698c2010-09-01T00:00:00Zhttps://www.dia-endojournals.ru/jour/article/view/5485https://doaj.org/toc/2072-0351https://doaj.org/toc/2072-0378Aim. To study the role of vascular endothelial growth factor (VEGF-A) in the fluid of the anterior chamber of the eye (ACE) in the evolvement ofdiabetic retinopathy (DR) and the outcome of cataract surgery. Materials and methods. The study included 120 patients with diabetes mellitus (DM) operated for the removal of cataract. 16 patients received treatmentfor DR-related neovascular glaucoma (NG). The control group comprised 22 subjects without DM. VEGF-A and glucose levels were measuredin the ACE fluid prior to surgery. Results. Patients with DM were not significantly different in terms of VEGF-A, fasting glucose, and HbA1c levels on the day of surgery excepting DMpatients without DR. VEGF-A and glucose levels in AEG increased in proportion to DR severity. VEGF-A concentration was minimal in the absenceof DR (22.75 pg/ml [10.78; 63.36]) and amounted to 336.6 pg/ml [232.3; 410.74] in patients with DM and DR (PAnatoliy Gennad'evich Kuz'minDmitriy Valentinovich LipatovTimofey Alexandrovich ChistyakovOlga Mikhailovna SmirnovaMargarita Ivanovna ArbuzovaAlexander Viktorovich Il'inMarina Vladimirovna ShestakovaEndocrinology Research Centrearticlevegfvascular endothelial growth factor (vegf-a)diabetic retinopathycataractcataract surgeryNutritional diseases. Deficiency diseasesRC620-627ENRUСахарный диабет, Vol 13, Iss 3, Pp 32-36 (2010)
institution	DOAJ
collection	DOAJ
language	EN RU
topic	vegf vascular endothelial growth factor (vegf-a) diabetic retinopathy cataract cataract surgery Nutritional diseases. Deficiency diseases RC620-627
spellingShingle	vegf vascular endothelial growth factor (vegf-a) diabetic retinopathy cataract cataract surgery Nutritional diseases. Deficiency diseases RC620-627 Anatoliy Gennad'evich Kuz'min Dmitriy Valentinovich Lipatov Timofey Alexandrovich Chistyakov Olga Mikhailovna Smirnova Margarita Ivanovna Arbuzova Alexander Viktorovich Il'in Marina Vladimirovna Shestakova Vascular endothelial growth factor in the fluid of the anterior chamber of the eye in patients with diabetic retinopathy, cataract andneovascular glaucoma
description	Aim. To study the role of vascular endothelial growth factor (VEGF-A) in the fluid of the anterior chamber of the eye (ACE) in the evolvement ofdiabetic retinopathy (DR) and the outcome of cataract surgery. Materials and methods. The study included 120 patients with diabetes mellitus (DM) operated for the removal of cataract. 16 patients received treatmentfor DR-related neovascular glaucoma (NG). The control group comprised 22 subjects without DM. VEGF-A and glucose levels were measuredin the ACE fluid prior to surgery. Results. Patients with DM were not significantly different in terms of VEGF-A, fasting glucose, and HbA1c levels on the day of surgery excepting DMpatients without DR. VEGF-A and glucose levels in AEG increased in proportion to DR severity. VEGF-A concentration was minimal in the absenceof DR (22.75 pg/ml [10.78; 63.36]) and amounted to 336.6 pg/ml [232.3; 410.74] in patients with DM and DR (P
format	article
author	Anatoliy Gennad'evich Kuz'min Dmitriy Valentinovich Lipatov Timofey Alexandrovich Chistyakov Olga Mikhailovna Smirnova Margarita Ivanovna Arbuzova Alexander Viktorovich Il'in Marina Vladimirovna Shestakova
author_facet	Anatoliy Gennad'evich Kuz'min Dmitriy Valentinovich Lipatov Timofey Alexandrovich Chistyakov Olga Mikhailovna Smirnova Margarita Ivanovna Arbuzova Alexander Viktorovich Il'in Marina Vladimirovna Shestakova
author_sort	Anatoliy Gennad'evich Kuz'min
title	Vascular endothelial growth factor in the fluid of the anterior chamber of the eye in patients with diabetic retinopathy, cataract andneovascular glaucoma
title_short	Vascular endothelial growth factor in the fluid of the anterior chamber of the eye in patients with diabetic retinopathy, cataract andneovascular glaucoma
title_full	Vascular endothelial growth factor in the fluid of the anterior chamber of the eye in patients with diabetic retinopathy, cataract andneovascular glaucoma
title_fullStr	Vascular endothelial growth factor in the fluid of the anterior chamber of the eye in patients with diabetic retinopathy, cataract andneovascular glaucoma
title_full_unstemmed	Vascular endothelial growth factor in the fluid of the anterior chamber of the eye in patients with diabetic retinopathy, cataract andneovascular glaucoma
title_sort	vascular endothelial growth factor in the fluid of the anterior chamber of the eye in patients with diabetic retinopathy, cataract andneovascular glaucoma
publisher	Endocrinology Research Centre
publishDate	2010
url	https://doaj.org/article/fa064ce190a048269adcb491be8b698c
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Vascular endothelial growth factor in the fluid of the anterior chamber of the eye in patients with diabetic retinopathy, cataract andneovascular glaucoma

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