Induced Packaging of Cellular MicroRNAs into HIV-1 Virions Can Inhibit Infectivity

ABSTRACT Analysis of the incorporation of cellular microRNAs (miRNAs) into highly purified HIV-1 virions revealed that this largely, but not entirely, mirrored the level of miRNA expression in the producer CD4+ T cells. Specifically, of the 58 cellular miRNAs detected at significant levels in the pr...

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Autores principales: Hal P. Bogerd, Edward M. Kennedy, Adam W. Whisnant, Bryan R. Cullen
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2017
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Acceso en línea:https://doaj.org/article/fa069fe78e4a48ef9bd34dcaee41438c
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