Prescribing errors involving antineoplastics and others drug centre of preparation of injectable drugs

Objective: To describe the prescribing errors involving antineoplastics and others drugs in a centre for the preparation of injectable drugs at a university hospital. Method: A retrospective descriptive study was carried out based on the records of a drug preparation center with prescribing errors...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Luciana SANTOS, Thalita JACOBY, Sandro NESS, Gérson GUERRA, Carlos A. WAYHS
Formato:	article
Lenguaje:	EN PT
Publicado:	Sociedade Brasileira de Farmácia Hospitalar e Serviços de Saúde 2020
Materias:	Public aspects of medicine RA1-1270 Pharmacy and materia medica RS1-441 Therapeutics. Pharmacology RM1-950
Acceso en línea:	https://doaj.org/article/fa1be64eb82144fcb4e8c23a984c8fad
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:fa1be64eb82144fcb4e8c23a984c8fad
record_format	dspace
spelling	oai:doaj.org-article:fa1be64eb82144fcb4e8c23a984c8fad2021-11-28T02:45:09ZPrescribing errors involving antineoplastics and others drug centre of preparation of injectable drugs10.30968/rbfhss.2020.111.03352179-59242316-7750https://doaj.org/article/fa1be64eb82144fcb4e8c23a984c8fad2020-07-01T00:00:00Zhttps://www.rbfhss.org.br/sbrafh/article/view/335https://doaj.org/toc/2179-5924https://doaj.org/toc/2316-7750 Objective: To describe the prescribing errors involving antineoplastics and others drugs in a centre for the preparation of injectable drugs at a university hospital. Method: A retrospective descriptive study was carried out based on the records of a drug preparation center with prescribing errors identified in the pharmaceutical validation phase prior to drug preparation in the period from 2016 to 2017.Results: A total of 1516 prescriptions/month were evaluated and 562 prescribing errors were identified and the prescription error rate involving medications was 1.5%. Of the drugs most involved in errors are cisplatin (37.5%), etoposide (14.1%), carboplatin (8.9%), cyclophosphamide (5.7%) and oxaliplatin (4.1%). Most of the errors were related to the diluents associated with the preparations, either in the absence of this information or in the prescription of volumes outside the concentration range required by the preparation of the drug with 56% and 22.6% respectively. In 94.3% of the prescriptions identified with errors, pharmaceutical interventions were necessary for its correction before preparation with adhesion in 99.6% of the cases. Conclusion: Although prescribing errors are described in the literature, the study presents the fragility of the prescriber system, even when it is computerized, and the importance of organized barriers or processes to avoid errors of prescription and manipulation in a centre for the preparation of injectable drugs Luciana SANTOSThalita JACOBYSandro NESSGérson GUERRACarlos A. WAYHSSociedade Brasileira de Farmácia Hospitalar e Serviços de SaúdearticlePublic aspects of medicineRA1-1270Pharmacy and materia medicaRS1-441Therapeutics. PharmacologyRM1-950ENPTRevista Brasileira de Farmácia Hospitalar e Serviços de Saúde, Vol 11, Iss 1 (2020)
institution	DOAJ
collection	DOAJ
language	EN PT
topic	Public aspects of medicine RA1-1270 Pharmacy and materia medica RS1-441 Therapeutics. Pharmacology RM1-950
spellingShingle	Public aspects of medicine RA1-1270 Pharmacy and materia medica RS1-441 Therapeutics. Pharmacology RM1-950 Luciana SANTOS Thalita JACOBY Sandro NESS Gérson GUERRA Carlos A. WAYHS Prescribing errors involving antineoplastics and others drug centre of preparation of injectable drugs
description	Objective: To describe the prescribing errors involving antineoplastics and others drugs in a centre for the preparation of injectable drugs at a university hospital. Method: A retrospective descriptive study was carried out based on the records of a drug preparation center with prescribing errors identified in the pharmaceutical validation phase prior to drug preparation in the period from 2016 to 2017.Results: A total of 1516 prescriptions/month were evaluated and 562 prescribing errors were identified and the prescription error rate involving medications was 1.5%. Of the drugs most involved in errors are cisplatin (37.5%), etoposide (14.1%), carboplatin (8.9%), cyclophosphamide (5.7%) and oxaliplatin (4.1%). Most of the errors were related to the diluents associated with the preparations, either in the absence of this information or in the prescription of volumes outside the concentration range required by the preparation of the drug with 56% and 22.6% respectively. In 94.3% of the prescriptions identified with errors, pharmaceutical interventions were necessary for its correction before preparation with adhesion in 99.6% of the cases. Conclusion: Although prescribing errors are described in the literature, the study presents the fragility of the prescriber system, even when it is computerized, and the importance of organized barriers or processes to avoid errors of prescription and manipulation in a centre for the preparation of injectable drugs
format	article
author	Luciana SANTOS Thalita JACOBY Sandro NESS Gérson GUERRA Carlos A. WAYHS
author_facet	Luciana SANTOS Thalita JACOBY Sandro NESS Gérson GUERRA Carlos A. WAYHS
author_sort	Luciana SANTOS
title	Prescribing errors involving antineoplastics and others drug centre of preparation of injectable drugs
title_short	Prescribing errors involving antineoplastics and others drug centre of preparation of injectable drugs
title_full	Prescribing errors involving antineoplastics and others drug centre of preparation of injectable drugs
title_fullStr	Prescribing errors involving antineoplastics and others drug centre of preparation of injectable drugs
title_full_unstemmed	Prescribing errors involving antineoplastics and others drug centre of preparation of injectable drugs
title_sort	prescribing errors involving antineoplastics and others drug centre of preparation of injectable drugs
publisher	Sociedade Brasileira de Farmácia Hospitalar e Serviços de Saúde
publishDate	2020
url	https://doaj.org/article/fa1be64eb82144fcb4e8c23a984c8fad
work_keys_str_mv	AT lucianasantos prescribingerrorsinvolvingantineoplasticsandothersdrugcentreofpreparationofinjectabledrugs AT thalitajacoby prescribingerrorsinvolvingantineoplasticsandothersdrugcentreofpreparationofinjectabledrugs AT sandroness prescribingerrorsinvolvingantineoplasticsandothersdrugcentreofpreparationofinjectabledrugs AT gersonguerra prescribingerrorsinvolvingantineoplasticsandothersdrugcentreofpreparationofinjectabledrugs AT carlosawayhs prescribingerrorsinvolvingantineoplasticsandothersdrugcentreofpreparationofinjectabledrugs
_version_	1718408477984948224

Prescribing errors involving antineoplastics and others drug centre of preparation of injectable drugs

Ejemplares similares