Targeting the neurokinin receptor 1 with aprepitant: a novel antipruritic strategy.
<h4>Background</h4>Chronic pruritus is a global clinical problem with a high impact on the quality of life and lack of specific therapies. It is an excruciating and frequent symptom of e.g. uncurable renal, liver and skin diseases which often does not respond to conventional treatment wi...
Guardado en:
Autores principales: | Sonja Ständer, Dorothee Siepmann, Ilka Herrgott, Cord Sunderkötter, Thomas A Luger |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2010
|
Materias: | |
Acceso en línea: | https://doaj.org/article/fa1def7bcaaf45d891b3ab7797963232 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Human substance P receptor binding mode of the antagonist drug aprepitant by NMR and crystallography
por: Shuanghong Chen, et al.
Publicado: (2019) -
Crystal structures of the human neurokinin 1 receptor in complex with clinically used antagonists
por: Jendrik Schöppe, et al.
Publicado: (2019) -
Substance P/ Neurokinin-1 Receptor, Trigeminal Ganglion, Latency, and Coronavirus Infection-Is There Any Link?
por: Riffat Mehboob, et al.
Publicado: (2021) -
Antinociceptive and Antipruritic Effects of HSK21542, a Peripherally-Restricted Kappa Opioid Receptor Agonist, in Animal Models of Pain and Itch
por: Xin Wang, et al.
Publicado: (2021) -
Neurokinin-3 receptor activation selectively prolongs atrial refractoriness by inhibition of a background K+ channel
por: Marieke W. Veldkamp, et al.
Publicado: (2018)