CRISPR artificial splicing factors

Control over splicing could be used for both therapeutic and engineering applications. Here the authors create artificial splicing factors using RNA-targeting CRISPR systems under small molecule control.

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Autores principales: Menghan Du, Nathaniel Jillette, Jacqueline Jufen Zhu, Sheng Li, Albert Wu Cheng
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/fa264e04819c4745a7fbdb519bfa799a
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spelling oai:doaj.org-article:fa264e04819c4745a7fbdb519bfa799a2021-12-02T17:47:59ZCRISPR artificial splicing factors10.1038/s41467-020-16806-42041-1723https://doaj.org/article/fa264e04819c4745a7fbdb519bfa799a2020-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-16806-4https://doaj.org/toc/2041-1723Control over splicing could be used for both therapeutic and engineering applications. Here the authors create artificial splicing factors using RNA-targeting CRISPR systems under small molecule control.Menghan DuNathaniel JilletteJacqueline Jufen ZhuSheng LiAlbert Wu ChengNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Menghan Du
Nathaniel Jillette
Jacqueline Jufen Zhu
Sheng Li
Albert Wu Cheng
CRISPR artificial splicing factors
description Control over splicing could be used for both therapeutic and engineering applications. Here the authors create artificial splicing factors using RNA-targeting CRISPR systems under small molecule control.
format article
author Menghan Du
Nathaniel Jillette
Jacqueline Jufen Zhu
Sheng Li
Albert Wu Cheng
author_facet Menghan Du
Nathaniel Jillette
Jacqueline Jufen Zhu
Sheng Li
Albert Wu Cheng
author_sort Menghan Du
title CRISPR artificial splicing factors
title_short CRISPR artificial splicing factors
title_full CRISPR artificial splicing factors
title_fullStr CRISPR artificial splicing factors
title_full_unstemmed CRISPR artificial splicing factors
title_sort crispr artificial splicing factors
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/fa264e04819c4745a7fbdb519bfa799a
work_keys_str_mv AT menghandu crisprartificialsplicingfactors
AT nathanieljillette crisprartificialsplicingfactors
AT jacquelinejufenzhu crisprartificialsplicingfactors
AT shengli crisprartificialsplicingfactors
AT albertwucheng crisprartificialsplicingfactors
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