Accurate high throughput alignment via line sweep-based seed processing

Alignment is an important stage in the analysis of sequencing data. Here, the authors present a fast and accurate alignment approach suitable for long and short reads, and introduce two line sweep-based techniques which can replace the often-used chaining approach.

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Detalles Bibliográficos
Autores principales: Markus Schmidt, Klaus Heese, Arne Kutzner
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/fa27a9d32d6e484088cd6883e0fc34c1
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Descripción
Sumario:Alignment is an important stage in the analysis of sequencing data. Here, the authors present a fast and accurate alignment approach suitable for long and short reads, and introduce two line sweep-based techniques which can replace the often-used chaining approach.