Accurate high throughput alignment via line sweep-based seed processing

Alignment is an important stage in the analysis of sequencing data. Here, the authors present a fast and accurate alignment approach suitable for long and short reads, and introduce two line sweep-based techniques which can replace the often-used chaining approach.

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Détails bibliographiques
Auteurs principaux: Markus Schmidt, Klaus Heese, Arne Kutzner
Format: article
Langue:EN
Publié: Nature Portfolio 2019
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Accès en ligne:https://doaj.org/article/fa27a9d32d6e484088cd6883e0fc34c1
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Description
Résumé:Alignment is an important stage in the analysis of sequencing data. Here, the authors present a fast and accurate alignment approach suitable for long and short reads, and introduce two line sweep-based techniques which can replace the often-used chaining approach.