Accurate high throughput alignment via line sweep-based seed processing

Alignment is an important stage in the analysis of sequencing data. Here, the authors present a fast and accurate alignment approach suitable for long and short reads, and introduce two line sweep-based techniques which can replace the often-used chaining approach.

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Detalles Bibliográficos
Autores principales:	Markus Schmidt, Klaus Heese, Arne Kutzner
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/fa27a9d32d6e484088cd6883e0fc34c1
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spelling	oai:doaj.org-article:fa27a9d32d6e484088cd6883e0fc34c12021-12-02T16:57:33ZAccurate high throughput alignment via line sweep-based seed processing10.1038/s41467-019-09977-22041-1723https://doaj.org/article/fa27a9d32d6e484088cd6883e0fc34c12019-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-09977-2https://doaj.org/toc/2041-1723Alignment is an important stage in the analysis of sequencing data. Here, the authors present a fast and accurate alignment approach suitable for long and short reads, and introduce two line sweep-based techniques which can replace the often-used chaining approach.Markus SchmidtKlaus HeeseArne KutznerNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Markus Schmidt Klaus Heese Arne Kutzner Accurate high throughput alignment via line sweep-based seed processing
description	Alignment is an important stage in the analysis of sequencing data. Here, the authors present a fast and accurate alignment approach suitable for long and short reads, and introduce two line sweep-based techniques which can replace the often-used chaining approach.
format	article
author	Markus Schmidt Klaus Heese Arne Kutzner
author_facet	Markus Schmidt Klaus Heese Arne Kutzner
author_sort	Markus Schmidt
title	Accurate high throughput alignment via line sweep-based seed processing
title_short	Accurate high throughput alignment via line sweep-based seed processing
title_full	Accurate high throughput alignment via line sweep-based seed processing
title_fullStr	Accurate high throughput alignment via line sweep-based seed processing
title_full_unstemmed	Accurate high throughput alignment via line sweep-based seed processing
title_sort	accurate high throughput alignment via line sweep-based seed processing
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/fa27a9d32d6e484088cd6883e0fc34c1
work_keys_str_mv	AT markusschmidt accuratehighthroughputalignmentvialinesweepbasedseedprocessing AT klausheese accuratehighthroughputalignmentvialinesweepbasedseedprocessing AT arnekutzner accuratehighthroughputalignmentvialinesweepbasedseedprocessing
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Accurate high throughput alignment via line sweep-based seed processing

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