Gastric bypass surgery is followed by lowered blood pressure and increased diuresis - long term results from the Swedish Obese Subjects (SOS) study.
<h4>Objective</h4>To compare two bariatric surgical principles with regard to effects on blood pressure and salt intake.<h4>Background</h4>In most patients bariatric surgery induces a sustained weight loss and a reduced cardiovascular risk profile but the long-term effect on...
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2012
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oai:doaj.org-article:fa2cadd6a3ca415680bd4de719c7ce0f2021-11-18T08:07:09ZGastric bypass surgery is followed by lowered blood pressure and increased diuresis - long term results from the Swedish Obese Subjects (SOS) study.1932-620310.1371/journal.pone.0049696https://doaj.org/article/fa2cadd6a3ca415680bd4de719c7ce0f2012-01-01T00:00:00Zhttps://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23209592/?tool=EBIhttps://doaj.org/toc/1932-6203<h4>Objective</h4>To compare two bariatric surgical principles with regard to effects on blood pressure and salt intake.<h4>Background</h4>In most patients bariatric surgery induces a sustained weight loss and a reduced cardiovascular risk profile but the long-term effect on blood pressure is uncertain.<h4>Methods</h4>Cohort study with data from the prospective, controlled Swedish Obese Subjects (SOS) study involving 480 primary health care centres and 25 surgical departments in Sweden. Obese patients treated with non-surgical methods (Controls, n = 1636 and n = 1132 at 2 y and 10 y follow up, respectively) were compared to patients treated with gastric bypass (GBP, n = 245 and n = 277, respectively) or purely restrictive procedures (vertical banded gastroplasty or gastric banding; VBG/B, n = 1534 and n = 1064, respectively).<h4>Results</h4>At long-term follow-up (median 10 y) GBP was associated with lowered systolic (mean: -5.1 mm Hg) and diastolic pressure (-5.6 mmHg) differing significantly from both VBG/B (-1.5 and -2.1 mmHg, respectively; p<0.001) and Controls (+1.2 and -3.8 mmHg, respectively; p<0.01). Diurnal urinary output was +100 ml (P<0.05) and +170 ml (P<0.001) higher in GBP subjects than in weight-loss matched VBG/B subjects at the 2 y and 10 y follow-ups, respectively. Urinary output was linearly associated with blood pressure only after GBP and these patients consumed approximately 1 g salt per day more at the follow-ups than did VBG/B (P<0.01).<h4>Conclusions</h4>The purely restrictive techniques VBG/B exerted a transient blood pressure lowering effect, whereas gastric bypass was associated with a sustained blood pressure reduction and an increased diuresis. The daily salt consumption was higher after gastric bypass than after restrictive bariatric surgery.Peter HallersundLars SjöströmTorsten OlbersHans LönrothPeter JacobsonVille WalleniusIngmar NäslundLena M CarlssonLars FändriksPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 7, Iss 11, p e49696 (2012) |
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Medicine R Science Q Peter Hallersund Lars Sjöström Torsten Olbers Hans Lönroth Peter Jacobson Ville Wallenius Ingmar Näslund Lena M Carlsson Lars Fändriks Gastric bypass surgery is followed by lowered blood pressure and increased diuresis - long term results from the Swedish Obese Subjects (SOS) study. |
| description |
<h4>Objective</h4>To compare two bariatric surgical principles with regard to effects on blood pressure and salt intake.<h4>Background</h4>In most patients bariatric surgery induces a sustained weight loss and a reduced cardiovascular risk profile but the long-term effect on blood pressure is uncertain.<h4>Methods</h4>Cohort study with data from the prospective, controlled Swedish Obese Subjects (SOS) study involving 480 primary health care centres and 25 surgical departments in Sweden. Obese patients treated with non-surgical methods (Controls, n = 1636 and n = 1132 at 2 y and 10 y follow up, respectively) were compared to patients treated with gastric bypass (GBP, n = 245 and n = 277, respectively) or purely restrictive procedures (vertical banded gastroplasty or gastric banding; VBG/B, n = 1534 and n = 1064, respectively).<h4>Results</h4>At long-term follow-up (median 10 y) GBP was associated with lowered systolic (mean: -5.1 mm Hg) and diastolic pressure (-5.6 mmHg) differing significantly from both VBG/B (-1.5 and -2.1 mmHg, respectively; p<0.001) and Controls (+1.2 and -3.8 mmHg, respectively; p<0.01). Diurnal urinary output was +100 ml (P<0.05) and +170 ml (P<0.001) higher in GBP subjects than in weight-loss matched VBG/B subjects at the 2 y and 10 y follow-ups, respectively. Urinary output was linearly associated with blood pressure only after GBP and these patients consumed approximately 1 g salt per day more at the follow-ups than did VBG/B (P<0.01).<h4>Conclusions</h4>The purely restrictive techniques VBG/B exerted a transient blood pressure lowering effect, whereas gastric bypass was associated with a sustained blood pressure reduction and an increased diuresis. The daily salt consumption was higher after gastric bypass than after restrictive bariatric surgery. |
| format |
article |
| author |
Peter Hallersund Lars Sjöström Torsten Olbers Hans Lönroth Peter Jacobson Ville Wallenius Ingmar Näslund Lena M Carlsson Lars Fändriks |
| author_facet |
Peter Hallersund Lars Sjöström Torsten Olbers Hans Lönroth Peter Jacobson Ville Wallenius Ingmar Näslund Lena M Carlsson Lars Fändriks |
| author_sort |
Peter Hallersund |
| title |
Gastric bypass surgery is followed by lowered blood pressure and increased diuresis - long term results from the Swedish Obese Subjects (SOS) study. |
| title_short |
Gastric bypass surgery is followed by lowered blood pressure and increased diuresis - long term results from the Swedish Obese Subjects (SOS) study. |
| title_full |
Gastric bypass surgery is followed by lowered blood pressure and increased diuresis - long term results from the Swedish Obese Subjects (SOS) study. |
| title_fullStr |
Gastric bypass surgery is followed by lowered blood pressure and increased diuresis - long term results from the Swedish Obese Subjects (SOS) study. |
| title_full_unstemmed |
Gastric bypass surgery is followed by lowered blood pressure and increased diuresis - long term results from the Swedish Obese Subjects (SOS) study. |
| title_sort |
gastric bypass surgery is followed by lowered blood pressure and increased diuresis - long term results from the swedish obese subjects (sos) study. |
| publisher |
Public Library of Science (PLoS) |
| publishDate |
2012 |
| url |
https://doaj.org/article/fa2cadd6a3ca415680bd4de719c7ce0f |
| work_keys_str_mv |
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