Network meta-analysis for clinicians
Decision making in clinical practice requires consideration of the relative efficacy and safety of medical interventions. A systematic review and meta-analysis, the results of which have the highest level of confidence in evidence-based medicine, only compare the effectiveness of two interventions,...
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IP Habib O.N.
2021
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| Acceso en línea: | https://doaj.org/article/fa2deff846204e8e9fb53c4c9515d510 |
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oai:doaj.org-article:fa2deff846204e8e9fb53c4c9515d5102021-11-30T16:55:01ZNetwork meta-analysis for clinicians1815-14341815-144210.26442/18151434.2021.3.201202https://doaj.org/article/fa2deff846204e8e9fb53c4c9515d5102021-11-01T00:00:00Zhttps://modernonco.orscience.ru/1815-1434/article/viewFile/88099/66223https://doaj.org/toc/1815-1434https://doaj.org/toc/1815-1442Decision making in clinical practice requires consideration of the relative efficacy and safety of medical interventions. A systematic review and meta-analysis, the results of which have the highest level of confidence in evidence-based medicine, only compare the effectiveness of two interventions, provided that there is a direct comparison between them in a set of randomized controlled trials. The development of statistical methods has led to the development of the network meta-analysis method, the application of which allows comparison for more than two interventions and even if the interventions were not directly compared in randomized controlled trials, but have a common comparison intervention. As a result, network meta-analysis is increasingly being used as an evidence base for the effectiveness of medical interventions. However, there are important assumptions and conditions underlying the performance of network meta-analysis. In this work, we tried to outline the main aspects of network meta-analysis that are important for clinicians in terms of its implementation and interpretation of its results.Alexey A. BogdanovAndrey A. BogdanovIP Habib O.N.articleevidence-based medicinecomparative effectiveness of medical interventionsnetwork meta-analysisNeoplasms. Tumors. Oncology. Including cancer and carcinogensRC254-282RUСовременная онкология, Vol 23, Iss 3, Pp 418-424 (2021) |
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DOAJ |
| collection |
DOAJ |
| language |
RU |
| topic |
evidence-based medicine comparative effectiveness of medical interventions network meta-analysis Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282 |
| spellingShingle |
evidence-based medicine comparative effectiveness of medical interventions network meta-analysis Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282 Alexey A. Bogdanov Andrey A. Bogdanov Network meta-analysis for clinicians |
| description |
Decision making in clinical practice requires consideration of the relative efficacy and safety of medical interventions. A systematic review and meta-analysis, the results of which have the highest level of confidence in evidence-based medicine, only compare the effectiveness of two interventions, provided that there is a direct comparison between them in a set of randomized controlled trials. The development of statistical methods has led to the development of the network meta-analysis method, the application of which allows comparison for more than two interventions and even if the interventions were not directly compared in randomized controlled trials, but have a common comparison intervention. As a result, network meta-analysis is increasingly being used as an evidence base for the effectiveness of medical interventions. However, there are important assumptions and conditions underlying the performance of network meta-analysis. In this work, we tried to outline the main aspects of network meta-analysis that are important for clinicians in terms of its implementation and interpretation of its results. |
| format |
article |
| author |
Alexey A. Bogdanov Andrey A. Bogdanov |
| author_facet |
Alexey A. Bogdanov Andrey A. Bogdanov |
| author_sort |
Alexey A. Bogdanov |
| title |
Network meta-analysis for clinicians |
| title_short |
Network meta-analysis for clinicians |
| title_full |
Network meta-analysis for clinicians |
| title_fullStr |
Network meta-analysis for clinicians |
| title_full_unstemmed |
Network meta-analysis for clinicians |
| title_sort |
network meta-analysis for clinicians |
| publisher |
IP Habib O.N. |
| publishDate |
2021 |
| url |
https://doaj.org/article/fa2deff846204e8e9fb53c4c9515d510 |
| work_keys_str_mv |
AT alexeyabogdanov networkmetaanalysisforclinicians AT andreyabogdanov networkmetaanalysisforclinicians |
| _version_ |
1718406479887728640 |