The Long Noncoding RNA <italic toggle="yes">HEAL</italic> Regulates HIV-1 Replication through Epigenetic Regulation of the HIV-1 Promoter

The Long Noncoding RNA <italic toggle="yes">HEAL</italic> Regulates HIV-1 Replication through Epigenetic Regulation of the HIV-1 Promoter

ABSTRACT A major challenge in finding a cure for HIV-1/AIDS is the difficulty in identifying and eradicating persistent reservoirs of replication-competent provirus. Long noncoding RNAs (lncRNAs, >200 nucleotides) are increasingly recognized to play important roles in pathophysiology. Here, we re...

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Bibliographic Details
Main Authors: Ti-Chun Chao, Qiong Zhang, Zhonghan Li, Shashi Kant Tiwari, Yue Qin, Edwin Yau, Ana Sanchez, Gatikrushna Singh, Kungyen Chang, Marcus Kaul, Maile Ann Young Karris, Tariq M. Rana
Format: article
Language:EN
Published: American Society for Microbiology 2019
Subjects:
long noncoding RNAs
epigenetic regulation
HIV promoter
ribonucleoprotein complexes
prevention of HIV-1 recrudescence
Microbiology
QR1-502
Online Access:https://doaj.org/article/fa30d74df4fb4e569d0b0444f422b5ae
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https://doaj.org/article/fa30d74df4fb4e569d0b0444f422b5ae

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