Research highlights from the International Journal of Nanomedicine 2014
Sarah H Mian, Neel A Patel, Farina Shah, Sateesh B Arja, Farooq A ShiekhDepartment of Basic Medical Sciences, Avalon University School of Medicine, Curaçao, Netherlands AntillesCan nanocarriers conquer gene therapy?Evaluation of: Magalhães M, Farinha D, Pedroso de Lima MC, Fan...
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Dove Medical Press
2015
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oai:doaj.org-article:fa33212d9c7747bb807dfaabf7293d6b2021-12-02T05:09:41ZResearch highlights from the International Journal of Nanomedicine 20141178-2013https://doaj.org/article/fa33212d9c7747bb807dfaabf7293d6b2015-03-01T00:00:00Zhttp://www.dovepress.com/research-highlights-from-the-international-journalnbspof-nanomedicine--peer-reviewed-article-IJNhttps://doaj.org/toc/1178-2013 Sarah H Mian, Neel A Patel, Farina Shah, Sateesh B Arja, Farooq A ShiekhDepartment of Basic Medical Sciences, Avalon University School of Medicine, Curaçao, Netherlands AntillesCan nanocarriers conquer gene therapy?Evaluation of: Magalhães M, Farinha D, Pedroso de Lima MC, Faneca H. Increased gene delivery efficiency and specificity of a lipid-based nanosystem incorporating a glycolipid. Int J Nanomedicine. 2014;9:4979–4989. Hepatocellular carcinoma (HCC) is a devastating disease that makes up 70%–85% of all cases of liver cancer, affecting millions of people worldwide.1 Unfortunately, HCC is aggressive and deadly; patients typically live for only 6 to 20 months after diagnosis, highlighting the dire need for new effective therapies. Although gene therapy has the potential to offer new biologically based medicines, the efficient, selective, and safe delivery of DNA- or RNA-based drugs to target cells including hepatocytes is still a major limiting factor to the broad applications of gene therapy in cancer diseases.2–4Mian SHPatel NAShah FArja SBShiekh FADove Medical PressarticleMedicine (General)R5-920ENInternational Journal of Nanomedicine, Vol 2015, Iss default, Pp 2503-2505 (2015) |
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Medicine (General) R5-920 Mian SH Patel NA Shah F Arja SB Shiekh FA Research highlights from the International Journal of Nanomedicine 2014 |
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Sarah H Mian, Neel A Patel, Farina Shah, Sateesh B Arja, Farooq A ShiekhDepartment of Basic Medical Sciences, Avalon University School of Medicine, Curaçao, Netherlands AntillesCan nanocarriers conquer gene therapy?Evaluation of: Magalhães M, Farinha D, Pedroso de Lima MC, Faneca H. Increased gene delivery efficiency and specificity of a lipid-based nanosystem incorporating a glycolipid. Int J Nanomedicine. 2014;9:4979–4989. Hepatocellular carcinoma (HCC) is a devastating disease that makes up 70%–85% of all cases of liver cancer, affecting millions of people worldwide.1 Unfortunately, HCC is aggressive and deadly; patients typically live for only 6 to 20 months after diagnosis, highlighting the dire need for new effective therapies. Although gene therapy has the potential to offer new biologically based medicines, the efficient, selective, and safe delivery of DNA- or RNA-based drugs to target cells including hepatocytes is still a major limiting factor to the broad applications of gene therapy in cancer diseases.2–4 |
format |
article |
author |
Mian SH Patel NA Shah F Arja SB Shiekh FA |
author_facet |
Mian SH Patel NA Shah F Arja SB Shiekh FA |
author_sort |
Mian SH |
title |
Research highlights from the International Journal of Nanomedicine 2014 |
title_short |
Research highlights from the International Journal of Nanomedicine 2014 |
title_full |
Research highlights from the International Journal of Nanomedicine 2014 |
title_fullStr |
Research highlights from the International Journal of Nanomedicine 2014 |
title_full_unstemmed |
Research highlights from the International Journal of Nanomedicine 2014 |
title_sort |
research highlights from the international journal of nanomedicine 2014 |
publisher |
Dove Medical Press |
publishDate |
2015 |
url |
https://doaj.org/article/fa33212d9c7747bb807dfaabf7293d6b |
work_keys_str_mv |
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