Human pancreatic beta-like cells converted from fibroblasts

Insulin-producing pancreatic beta cells, generatedin vitro, could lead to new anti-diabetic therapies. Here, Zhu et al. convert human fibroblasts into endodermal progenitors that differentiate in vitrointo glucose-responsive beta-like cells that, following transplantation in mice, protect from diabe...

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Autores principales:	Saiyong Zhu, Holger A. Russ, Xiaojing Wang, Mingliang Zhang, Tianhua Ma, Tao Xu, Shibing Tang, Matthias Hebrok, Sheng Ding
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/fa33db95f6a9413bb111300ab70dee0c
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spelling	oai:doaj.org-article:fa33db95f6a9413bb111300ab70dee0c2021-12-02T15:35:41ZHuman pancreatic beta-like cells converted from fibroblasts10.1038/ncomms100802041-1723https://doaj.org/article/fa33db95f6a9413bb111300ab70dee0c2016-01-01T00:00:00Zhttps://doi.org/10.1038/ncomms10080https://doaj.org/toc/2041-1723Insulin-producing pancreatic beta cells, generatedin vitro, could lead to new anti-diabetic therapies. Here, Zhu et al. convert human fibroblasts into endodermal progenitors that differentiate in vitrointo glucose-responsive beta-like cells that, following transplantation in mice, protect from diabetes.Saiyong ZhuHolger A. RussXiaojing WangMingliang ZhangTianhua MaTao XuShibing TangMatthias HebrokSheng DingNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Saiyong Zhu Holger A. Russ Xiaojing Wang Mingliang Zhang Tianhua Ma Tao Xu Shibing Tang Matthias Hebrok Sheng Ding Human pancreatic beta-like cells converted from fibroblasts
description	Insulin-producing pancreatic beta cells, generatedin vitro, could lead to new anti-diabetic therapies. Here, Zhu et al. convert human fibroblasts into endodermal progenitors that differentiate in vitrointo glucose-responsive beta-like cells that, following transplantation in mice, protect from diabetes.
format	article
author	Saiyong Zhu Holger A. Russ Xiaojing Wang Mingliang Zhang Tianhua Ma Tao Xu Shibing Tang Matthias Hebrok Sheng Ding
author_facet	Saiyong Zhu Holger A. Russ Xiaojing Wang Mingliang Zhang Tianhua Ma Tao Xu Shibing Tang Matthias Hebrok Sheng Ding
author_sort	Saiyong Zhu
title	Human pancreatic beta-like cells converted from fibroblasts
title_short	Human pancreatic beta-like cells converted from fibroblasts
title_full	Human pancreatic beta-like cells converted from fibroblasts
title_fullStr	Human pancreatic beta-like cells converted from fibroblasts
title_full_unstemmed	Human pancreatic beta-like cells converted from fibroblasts
title_sort	human pancreatic beta-like cells converted from fibroblasts
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/fa33db95f6a9413bb111300ab70dee0c
work_keys_str_mv	AT saiyongzhu humanpancreaticbetalikecellsconvertedfromfibroblasts AT holgeraruss humanpancreaticbetalikecellsconvertedfromfibroblasts AT xiaojingwang humanpancreaticbetalikecellsconvertedfromfibroblasts AT mingliangzhang humanpancreaticbetalikecellsconvertedfromfibroblasts AT tianhuama humanpancreaticbetalikecellsconvertedfromfibroblasts AT taoxu humanpancreaticbetalikecellsconvertedfromfibroblasts AT shibingtang humanpancreaticbetalikecellsconvertedfromfibroblasts AT matthiashebrok humanpancreaticbetalikecellsconvertedfromfibroblasts AT shengding humanpancreaticbetalikecellsconvertedfromfibroblasts
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Human pancreatic beta-like cells converted from fibroblasts

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