Enhancing the power of genetic association studies through the use of silver standard cases derived from electronic medical records.

Enhancing the power of genetic association studies through the use of silver standard cases derived from electronic medical records.

The feasibility of using imperfectly phenotyped "silver standard" samples identified from electronic medical record diagnoses is considered in genetic association studies when these samples might be combined with an existing set of samples phenotyped with a gold standard technique. An anal...

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Autores principales: Andrew McDavid, Paul K Crane, Katherine M Newton, David R Crosslin, Wayne McCormick, Noah Weston, Kelly Ehrlich, Eugene Hart, Robert Harrison, Walter A Kukull, Carla Rottscheit, Peggy Peissig, Elisha Stefanski, Catherine A McCarty, Rebecca Lynn Zuvich, Marylyn D Ritchie, Jonathan L Haines, Joshua C Denny, Gerard D Schellenberg, Mariza de Andrade, Iftikhar Kullo, Rongling Li, Daniel Mirel, Andrew Crenshaw, James D Bowen, Ge Li, Debby Tsuang, Susan McCurry, Linda Teri, Eric B Larson, Gail P Jarvik, Chris S Carlson
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/fa372963e31e49b88686fb2f6c50fec6
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