Lipid-mediated PX-BAR domain recruitment couples local membrane constriction to endocytic vesicle fission
The spatiotemporal regulation of membrane scaffolds recruitment and coupling between membrane deformation and fission in endocytosis are unclear. Here the authors show that lipid conversion at endocytic pits recruits SNX9, which couples local membrane constriction to fission in endocytosis.
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Nature Portfolio
2017
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oai:doaj.org-article:fa470d0995f64498b209d0b17a5941cb2021-12-02T15:38:53ZLipid-mediated PX-BAR domain recruitment couples local membrane constriction to endocytic vesicle fission10.1038/ncomms158732041-1723https://doaj.org/article/fa470d0995f64498b209d0b17a5941cb2017-06-01T00:00:00Zhttps://doi.org/10.1038/ncomms15873https://doaj.org/toc/2041-1723The spatiotemporal regulation of membrane scaffolds recruitment and coupling between membrane deformation and fission in endocytosis are unclear. Here the authors show that lipid conversion at endocytic pits recruits SNX9, which couples local membrane constriction to fission in endocytosis.Johannes SchönebergMartin LehmannAlexander UllrichYork PosorWen-Ting LoGregor LichtnerJan SchmoranzerVolker HauckeFrank NoéNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-17 (2017) |
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Science Q Johannes Schöneberg Martin Lehmann Alexander Ullrich York Posor Wen-Ting Lo Gregor Lichtner Jan Schmoranzer Volker Haucke Frank Noé Lipid-mediated PX-BAR domain recruitment couples local membrane constriction to endocytic vesicle fission |
description |
The spatiotemporal regulation of membrane scaffolds recruitment and coupling between membrane deformation and fission in endocytosis are unclear. Here the authors show that lipid conversion at endocytic pits recruits SNX9, which couples local membrane constriction to fission in endocytosis. |
format |
article |
author |
Johannes Schöneberg Martin Lehmann Alexander Ullrich York Posor Wen-Ting Lo Gregor Lichtner Jan Schmoranzer Volker Haucke Frank Noé |
author_facet |
Johannes Schöneberg Martin Lehmann Alexander Ullrich York Posor Wen-Ting Lo Gregor Lichtner Jan Schmoranzer Volker Haucke Frank Noé |
author_sort |
Johannes Schöneberg |
title |
Lipid-mediated PX-BAR domain recruitment couples local membrane constriction to endocytic vesicle fission |
title_short |
Lipid-mediated PX-BAR domain recruitment couples local membrane constriction to endocytic vesicle fission |
title_full |
Lipid-mediated PX-BAR domain recruitment couples local membrane constriction to endocytic vesicle fission |
title_fullStr |
Lipid-mediated PX-BAR domain recruitment couples local membrane constriction to endocytic vesicle fission |
title_full_unstemmed |
Lipid-mediated PX-BAR domain recruitment couples local membrane constriction to endocytic vesicle fission |
title_sort |
lipid-mediated px-bar domain recruitment couples local membrane constriction to endocytic vesicle fission |
publisher |
Nature Portfolio |
publishDate |
2017 |
url |
https://doaj.org/article/fa470d0995f64498b209d0b17a5941cb |
work_keys_str_mv |
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1718386088296316928 |