Lipid-mediated PX-BAR domain recruitment couples local membrane constriction to endocytic vesicle fission

The spatiotemporal regulation of membrane scaffolds recruitment and coupling between membrane deformation and fission in endocytosis are unclear. Here the authors show that lipid conversion at endocytic pits recruits SNX9, which couples local membrane constriction to fission in endocytosis.

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Autores principales: Johannes Schöneberg, Martin Lehmann, Alexander Ullrich, York Posor, Wen-Ting Lo, Gregor Lichtner, Jan Schmoranzer, Volker Haucke, Frank Noé
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Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/fa470d0995f64498b209d0b17a5941cb
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spelling oai:doaj.org-article:fa470d0995f64498b209d0b17a5941cb2021-12-02T15:38:53ZLipid-mediated PX-BAR domain recruitment couples local membrane constriction to endocytic vesicle fission10.1038/ncomms158732041-1723https://doaj.org/article/fa470d0995f64498b209d0b17a5941cb2017-06-01T00:00:00Zhttps://doi.org/10.1038/ncomms15873https://doaj.org/toc/2041-1723The spatiotemporal regulation of membrane scaffolds recruitment and coupling between membrane deformation and fission in endocytosis are unclear. Here the authors show that lipid conversion at endocytic pits recruits SNX9, which couples local membrane constriction to fission in endocytosis.Johannes SchönebergMartin LehmannAlexander UllrichYork PosorWen-Ting LoGregor LichtnerJan SchmoranzerVolker HauckeFrank NoéNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-17 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Johannes Schöneberg
Martin Lehmann
Alexander Ullrich
York Posor
Wen-Ting Lo
Gregor Lichtner
Jan Schmoranzer
Volker Haucke
Frank Noé
Lipid-mediated PX-BAR domain recruitment couples local membrane constriction to endocytic vesicle fission
description The spatiotemporal regulation of membrane scaffolds recruitment and coupling between membrane deformation and fission in endocytosis are unclear. Here the authors show that lipid conversion at endocytic pits recruits SNX9, which couples local membrane constriction to fission in endocytosis.
format article
author Johannes Schöneberg
Martin Lehmann
Alexander Ullrich
York Posor
Wen-Ting Lo
Gregor Lichtner
Jan Schmoranzer
Volker Haucke
Frank Noé
author_facet Johannes Schöneberg
Martin Lehmann
Alexander Ullrich
York Posor
Wen-Ting Lo
Gregor Lichtner
Jan Schmoranzer
Volker Haucke
Frank Noé
author_sort Johannes Schöneberg
title Lipid-mediated PX-BAR domain recruitment couples local membrane constriction to endocytic vesicle fission
title_short Lipid-mediated PX-BAR domain recruitment couples local membrane constriction to endocytic vesicle fission
title_full Lipid-mediated PX-BAR domain recruitment couples local membrane constriction to endocytic vesicle fission
title_fullStr Lipid-mediated PX-BAR domain recruitment couples local membrane constriction to endocytic vesicle fission
title_full_unstemmed Lipid-mediated PX-BAR domain recruitment couples local membrane constriction to endocytic vesicle fission
title_sort lipid-mediated px-bar domain recruitment couples local membrane constriction to endocytic vesicle fission
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/fa470d0995f64498b209d0b17a5941cb
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