Ciliary IFT80 balances canonical versus non-canonical hedgehog signalling for osteoblast differentiation

Primary cilia are highly conserved microtubule-based organelles that play essential roles in several cellular processes including osteogenesis. Here the authors show that intraflagellar protein IFT80 regulates osteoblast differentiation by balancing signalling though the canonical and non-canonical...

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Autores principales:	Xue Yuan, Jay Cao, Xiaoning He, Rosa Serra, Jun Qu, Xu Cao, Shuying Yang
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/fa47de65a8d94f02b609829c08f8d26e
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id	oai:doaj.org-article:fa47de65a8d94f02b609829c08f8d26e
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spelling	oai:doaj.org-article:fa47de65a8d94f02b609829c08f8d26e2021-12-02T17:32:38ZCiliary IFT80 balances canonical versus non-canonical hedgehog signalling for osteoblast differentiation10.1038/ncomms110242041-1723https://doaj.org/article/fa47de65a8d94f02b609829c08f8d26e2016-03-01T00:00:00Zhttps://doi.org/10.1038/ncomms11024https://doaj.org/toc/2041-1723Primary cilia are highly conserved microtubule-based organelles that play essential roles in several cellular processes including osteogenesis. Here the authors show that intraflagellar protein IFT80 regulates osteoblast differentiation by balancing signalling though the canonical and non-canonical Hedgehog pathways.Xue YuanJay CaoXiaoning HeRosa SerraJun QuXu CaoShuying YangNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Xue Yuan Jay Cao Xiaoning He Rosa Serra Jun Qu Xu Cao Shuying Yang Ciliary IFT80 balances canonical versus non-canonical hedgehog signalling for osteoblast differentiation
description	Primary cilia are highly conserved microtubule-based organelles that play essential roles in several cellular processes including osteogenesis. Here the authors show that intraflagellar protein IFT80 regulates osteoblast differentiation by balancing signalling though the canonical and non-canonical Hedgehog pathways.
format	article
author	Xue Yuan Jay Cao Xiaoning He Rosa Serra Jun Qu Xu Cao Shuying Yang
author_facet	Xue Yuan Jay Cao Xiaoning He Rosa Serra Jun Qu Xu Cao Shuying Yang
author_sort	Xue Yuan
title	Ciliary IFT80 balances canonical versus non-canonical hedgehog signalling for osteoblast differentiation
title_short	Ciliary IFT80 balances canonical versus non-canonical hedgehog signalling for osteoblast differentiation
title_full	Ciliary IFT80 balances canonical versus non-canonical hedgehog signalling for osteoblast differentiation
title_fullStr	Ciliary IFT80 balances canonical versus non-canonical hedgehog signalling for osteoblast differentiation
title_full_unstemmed	Ciliary IFT80 balances canonical versus non-canonical hedgehog signalling for osteoblast differentiation
title_sort	ciliary ift80 balances canonical versus non-canonical hedgehog signalling for osteoblast differentiation
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/fa47de65a8d94f02b609829c08f8d26e
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Ciliary IFT80 balances canonical versus non-canonical hedgehog signalling for osteoblast differentiation

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