Ciliary IFT80 balances canonical versus non-canonical hedgehog signalling for osteoblast differentiation

Ciliary IFT80 balances canonical versus non-canonical hedgehog signalling for osteoblast differentiation

Primary cilia are highly conserved microtubule-based organelles that play essential roles in several cellular processes including osteogenesis. Here the authors show that intraflagellar protein IFT80 regulates osteoblast differentiation by balancing signalling though the canonical and non-canonical...

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Bibliographic Details
Main Authors: Xue Yuan, Jay Cao, Xiaoning He, Rosa Serra, Jun Qu, Xu Cao, Shuying Yang
Format: article
Language:EN
Published: Nature Portfolio 2016
Subjects:
Science
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Online Access:https://doaj.org/article/fa47de65a8d94f02b609829c08f8d26e
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