A HML6 endogenous retrovirus on chromosome 3 is upregulated in amyotrophic lateral sclerosis motor cortex

A HML6 endogenous retrovirus on chromosome 3 is upregulated in amyotrophic lateral sclerosis motor cortex

Abstract There is increasing evidence that endogenous retroviruses (ERVs) play a significant role in central nervous system diseases, including amyotrophic lateral sclerosis (ALS). Studies of ALS have consistently identified retroviral enzyme reverse transcriptase activity in patients. Evidence indi...

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Bibliographic Details
Main Authors: Ashley R. Jones, Alfredo Iacoangeli, Brett N. Adey, Harry Bowles, Aleksey Shatunov, Claire Troakes, Jeremy A. Garson, Adele L. McCormick, Ammar Al-Chalabi
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
Medicine
R
Science
Q
Online Access:https://doaj.org/article/fa585c9e6ffc49b992d0f81a36717fb6
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