Long-term success of intravitreal bevacizumab for choroidal neovascularization associated with choroidal osteoma

Mariko Kubota-Taniai1,2, Toshiyuki Oshitari2, Maya Handa2, Takayuki Baba2, Jiro Yotsukura2, Shuichi Yamamoto21Department of Ophthalmology, National Hospital Organization, Chiba Medical Center, Chiba, Japan; 2Department of Ophthalmology and Visual Science, Chiba University Graduate School of Medicine...

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Autores principales:	Kubota-Taniai M, Oshitari T, Handa M, Baba T, Yotsukura J, Yamamoto S
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2011
Materias:	Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/fa5b5a06f3ea49388a2efa8d1086b8fa
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spelling	oai:doaj.org-article:fa5b5a06f3ea49388a2efa8d1086b8fa2021-12-02T03:35:10ZLong-term success of intravitreal bevacizumab for choroidal neovascularization associated with choroidal osteoma1177-54671177-5483https://doaj.org/article/fa5b5a06f3ea49388a2efa8d1086b8fa2011-07-01T00:00:00Zhttp://www.dovepress.com/long-term-success-of-intravitreal-bevacizumab-for-choroidal-neovascula-a7969https://doaj.org/toc/1177-5467https://doaj.org/toc/1177-5483Mariko Kubota-Taniai1,2, Toshiyuki Oshitari2, Maya Handa2, Takayuki Baba2, Jiro Yotsukura2, Shuichi Yamamoto21Department of Ophthalmology, National Hospital Organization, Chiba Medical Center, Chiba, Japan; 2Department of Ophthalmology and Visual Science, Chiba University Graduate School of Medicine, Chiba, JapanPurpose: To describe a case of choroidal osteoma with choroidal neovascularization (CNV) that was successfully treated with two intravitreal injections of bevacizumab (IVB).Design and methods: Case report on a 12-year-old Japanese girl who presented with a sudden decrease in vision in her left eye. At the first visit, 2 days after the onset of her symptoms, her visual acuity (VA) in her left eye was 0.2. Ophthalmoscopy showed a hemorrhage of 5 disc diameters under the retinal pigment epithelium and a serous retinal detachment at the posterior pole of the left eye. These findings were confirmed by optical coherence tomography. Fluorescein angiography (FA) and indocyanine green angiography (ICGA) showed several points of leakage around the fovea, which suggested a CNV. From these findings, the patient was diagnosed with choroidal osteoma with a CNV. The submacular hemorrhage was from the CNV associated with the choroidal osteoma. We treated her with two injections of 1.25 mg/0.05 mL IVB with a 4-month interval.Results: The patient&#39;s VA in her left eye improved to 0.7, and this vision was maintained for 4 years. The CNV disappeared in the FA and ICGA images and no recurrence was observed after 4 years.Conclusion: Our findings indicate that IVB is effective in resolving CNV in eyes with an osteoma and prevents a decrease of vision in eyes with a choroidal osteoma with a CNV.Keywords: choroidal osteoma, CNV, IVB, visual acuityKubota-Taniai MOshitari THanda MBaba TYotsukura JYamamoto SDove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2011, Iss default, Pp 1051-1055 (2011)
institution	DOAJ
collection	DOAJ
language	EN
topic	Ophthalmology RE1-994
spellingShingle	Ophthalmology RE1-994 Kubota-Taniai M Oshitari T Handa M Baba T Yotsukura J Yamamoto S Long-term success of intravitreal bevacizumab for choroidal neovascularization associated with choroidal osteoma
description	Mariko Kubota-Taniai1,2, Toshiyuki Oshitari2, Maya Handa2, Takayuki Baba2, Jiro Yotsukura2, Shuichi Yamamoto21Department of Ophthalmology, National Hospital Organization, Chiba Medical Center, Chiba, Japan; 2Department of Ophthalmology and Visual Science, Chiba University Graduate School of Medicine, Chiba, JapanPurpose: To describe a case of choroidal osteoma with choroidal neovascularization (CNV) that was successfully treated with two intravitreal injections of bevacizumab (IVB).Design and methods: Case report on a 12-year-old Japanese girl who presented with a sudden decrease in vision in her left eye. At the first visit, 2 days after the onset of her symptoms, her visual acuity (VA) in her left eye was 0.2. Ophthalmoscopy showed a hemorrhage of 5 disc diameters under the retinal pigment epithelium and a serous retinal detachment at the posterior pole of the left eye. These findings were confirmed by optical coherence tomography. Fluorescein angiography (FA) and indocyanine green angiography (ICGA) showed several points of leakage around the fovea, which suggested a CNV. From these findings, the patient was diagnosed with choroidal osteoma with a CNV. The submacular hemorrhage was from the CNV associated with the choroidal osteoma. We treated her with two injections of 1.25 mg/0.05 mL IVB with a 4-month interval.Results: The patient&#39;s VA in her left eye improved to 0.7, and this vision was maintained for 4 years. The CNV disappeared in the FA and ICGA images and no recurrence was observed after 4 years.Conclusion: Our findings indicate that IVB is effective in resolving CNV in eyes with an osteoma and prevents a decrease of vision in eyes with a choroidal osteoma with a CNV.Keywords: choroidal osteoma, CNV, IVB, visual acuity
format	article
author	Kubota-Taniai M Oshitari T Handa M Baba T Yotsukura J Yamamoto S
author_facet	Kubota-Taniai M Oshitari T Handa M Baba T Yotsukura J Yamamoto S
author_sort	Kubota-Taniai M
title	Long-term success of intravitreal bevacizumab for choroidal neovascularization associated with choroidal osteoma
title_short	Long-term success of intravitreal bevacizumab for choroidal neovascularization associated with choroidal osteoma
title_full	Long-term success of intravitreal bevacizumab for choroidal neovascularization associated with choroidal osteoma
title_fullStr	Long-term success of intravitreal bevacizumab for choroidal neovascularization associated with choroidal osteoma
title_full_unstemmed	Long-term success of intravitreal bevacizumab for choroidal neovascularization associated with choroidal osteoma
title_sort	long-term success of intravitreal bevacizumab for choroidal neovascularization associated with choroidal osteoma
publisher	Dove Medical Press
publishDate	2011
url	https://doaj.org/article/fa5b5a06f3ea49388a2efa8d1086b8fa
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Long-term success of intravitreal bevacizumab for choroidal neovascularization associated with choroidal osteoma

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