Directing curli polymerization with DNA origami nucleators

Directing curli polymerization with DNA origami nucleators

Curli are bacterial functional amyloids that have gained interest as self-assembling biomaterial for biotechnology applications. Here, the authors show that DNA origami decorated with CsgB nucleator proteins induced the site-specific nucleation and subsequent fibrillization of CsgA proteins.

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Autores principales: Xiuhai Mao, Ke Li, Mengmeng Liu, Xinyu Wang, Tianxin Zhao, Bolin An, Mengkui Cui, Yingfeng Li, Jiahua Pu, Jiang Li, Lihua Wang, Timothy K. Lu, Chunhai Fan, Chao Zhong
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/fa62fc4764634a9b9fded575c3944a52
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spelling oai:doaj.org-article:fa62fc4764634a9b9fded575c3944a522021-12-02T15:35:06ZDirecting curli polymerization with DNA origami nucleators10.1038/s41467-019-09369-62041-1723https://doaj.org/article/fa62fc4764634a9b9fded575c3944a522019-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-09369-6https://doaj.org/toc/2041-1723Curli are bacterial functional amyloids that have gained interest as self-assembling biomaterial for biotechnology applications. Here, the authors show that DNA origami decorated with CsgB nucleator proteins induced the site-specific nucleation and subsequent fibrillization of CsgA proteins.Xiuhai MaoKe LiMengmeng LiuXinyu WangTianxin ZhaoBolin AnMengkui CuiYingfeng LiJiahua PuJiang LiLihua WangTimothy K. LuChunhai FanChao ZhongNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Xiuhai Mao
Ke Li
Mengmeng Liu
Xinyu Wang
Tianxin Zhao
Bolin An
Mengkui Cui
Yingfeng Li
Jiahua Pu
Jiang Li
Lihua Wang
Timothy K. Lu
Chunhai Fan
Chao Zhong
Directing curli polymerization with DNA origami nucleators
description Curli are bacterial functional amyloids that have gained interest as self-assembling biomaterial for biotechnology applications. Here, the authors show that DNA origami decorated with CsgB nucleator proteins induced the site-specific nucleation and subsequent fibrillization of CsgA proteins.
format article
author Xiuhai Mao
Ke Li
Mengmeng Liu
Xinyu Wang
Tianxin Zhao
Bolin An
Mengkui Cui
Yingfeng Li
Jiahua Pu
Jiang Li
Lihua Wang
Timothy K. Lu
Chunhai Fan
Chao Zhong
author_facet Xiuhai Mao
Ke Li
Mengmeng Liu
Xinyu Wang
Tianxin Zhao
Bolin An
Mengkui Cui
Yingfeng Li
Jiahua Pu
Jiang Li
Lihua Wang
Timothy K. Lu
Chunhai Fan
Chao Zhong
author_sort Xiuhai Mao
title Directing curli polymerization with DNA origami nucleators
title_short Directing curli polymerization with DNA origami nucleators
title_full Directing curli polymerization with DNA origami nucleators
title_fullStr Directing curli polymerization with DNA origami nucleators
title_full_unstemmed Directing curli polymerization with DNA origami nucleators
title_sort directing curli polymerization with dna origami nucleators
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/fa62fc4764634a9b9fded575c3944a52
work_keys_str_mv AT xiuhaimao directingcurlipolymerizationwithdnaorigaminucleators
AT keli directingcurlipolymerizationwithdnaorigaminucleators
AT mengmengliu directingcurlipolymerizationwithdnaorigaminucleators
AT xinyuwang directingcurlipolymerizationwithdnaorigaminucleators
AT tianxinzhao directingcurlipolymerizationwithdnaorigaminucleators
AT bolinan directingcurlipolymerizationwithdnaorigaminucleators
AT mengkuicui directingcurlipolymerizationwithdnaorigaminucleators
AT yingfengli directingcurlipolymerizationwithdnaorigaminucleators
AT jiahuapu directingcurlipolymerizationwithdnaorigaminucleators
AT jiangli directingcurlipolymerizationwithdnaorigaminucleators
AT lihuawang directingcurlipolymerizationwithdnaorigaminucleators
AT timothyklu directingcurlipolymerizationwithdnaorigaminucleators
AT chunhaifan directingcurlipolymerizationwithdnaorigaminucleators
AT chaozhong directingcurlipolymerizationwithdnaorigaminucleators
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