Directing curli polymerization with DNA origami nucleators

Directing curli polymerization with DNA origami nucleators

Curli are bacterial functional amyloids that have gained interest as self-assembling biomaterial for biotechnology applications. Here, the authors show that DNA origami decorated with CsgB nucleator proteins induced the site-specific nucleation and subsequent fibrillization of CsgA proteins.

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Detalles Bibliográficos
Autores principales: Xiuhai Mao, Ke Li, Mengmeng Liu, Xinyu Wang, Tianxin Zhao, Bolin An, Mengkui Cui, Yingfeng Li, Jiahua Pu, Jiang Li, Lihua Wang, Timothy K. Lu, Chunhai Fan, Chao Zhong
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
Materias:
Science
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Acceso en línea:https://doaj.org/article/fa62fc4764634a9b9fded575c3944a52
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