Rational design of DNA nanostructures for single molecule biosensing

A key attribute for modern healthcare is the ability to detect low concentrations of biomarkers. Here, the authors use nanopores and DNA origami with target-specific aptamers for detection of CRP.

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Autores principales: Mukhil Raveendran, Andrew J. Lee, Rajan Sharma, Christoph Wälti, Paolo Actis
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/fa62fc6002844d50a62794d9b0816394
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spelling oai:doaj.org-article:fa62fc6002844d50a62794d9b08163942021-12-02T16:38:51ZRational design of DNA nanostructures for single molecule biosensing10.1038/s41467-020-18132-12041-1723https://doaj.org/article/fa62fc6002844d50a62794d9b08163942020-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-18132-1https://doaj.org/toc/2041-1723A key attribute for modern healthcare is the ability to detect low concentrations of biomarkers. Here, the authors use nanopores and DNA origami with target-specific aptamers for detection of CRP.Mukhil RaveendranAndrew J. LeeRajan SharmaChristoph WältiPaolo ActisNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Mukhil Raveendran
Andrew J. Lee
Rajan Sharma
Christoph Wälti
Paolo Actis
Rational design of DNA nanostructures for single molecule biosensing
description A key attribute for modern healthcare is the ability to detect low concentrations of biomarkers. Here, the authors use nanopores and DNA origami with target-specific aptamers for detection of CRP.
format article
author Mukhil Raveendran
Andrew J. Lee
Rajan Sharma
Christoph Wälti
Paolo Actis
author_facet Mukhil Raveendran
Andrew J. Lee
Rajan Sharma
Christoph Wälti
Paolo Actis
author_sort Mukhil Raveendran
title Rational design of DNA nanostructures for single molecule biosensing
title_short Rational design of DNA nanostructures for single molecule biosensing
title_full Rational design of DNA nanostructures for single molecule biosensing
title_fullStr Rational design of DNA nanostructures for single molecule biosensing
title_full_unstemmed Rational design of DNA nanostructures for single molecule biosensing
title_sort rational design of dna nanostructures for single molecule biosensing
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/fa62fc6002844d50a62794d9b0816394
work_keys_str_mv AT mukhilraveendran rationaldesignofdnananostructuresforsinglemoleculebiosensing
AT andrewjlee rationaldesignofdnananostructuresforsinglemoleculebiosensing
AT rajansharma rationaldesignofdnananostructuresforsinglemoleculebiosensing
AT christophwalti rationaldesignofdnananostructuresforsinglemoleculebiosensing
AT paoloactis rationaldesignofdnananostructuresforsinglemoleculebiosensing
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