Nuclear export and translation of circular repeat-containing intronic RNA in C9ORF72-ALS/FTD

Hexanucleotide repeat expansion in the intron 1 of the C9ORF72 gene can cause amyotrophic lateral sclerosis (ALS) and frontal temporal dementia (FTD). Here the authors use single molecule imaging to show nuclear export and translation of circular repeat-containing C9ORF72 intronic RNA.

Guardado en:

Detalles Bibliográficos
Autores principales:	Shaopeng Wang, Malgorzata J. Latallo, Zhe Zhang, Bo Huang, Dmitriy G. Bobrovnikov, Daoyuan Dong, Nathan M. Livingston, Wilson Tjoeng, Lindsey R. Hayes, Jeffrey D. Rothstein, Lyle W. Ostrow, Bin Wu, Shuying Sun
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/fa693cbc636a4db9b4b2a4b8bdc7fe5c
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:fa693cbc636a4db9b4b2a4b8bdc7fe5c
record_format	dspace
spelling	oai:doaj.org-article:fa693cbc636a4db9b4b2a4b8bdc7fe5c2021-12-02T16:27:56ZNuclear export and translation of circular repeat-containing intronic RNA in C9ORF72-ALS/FTD10.1038/s41467-021-25082-92041-1723https://doaj.org/article/fa693cbc636a4db9b4b2a4b8bdc7fe5c2021-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-25082-9https://doaj.org/toc/2041-1723Hexanucleotide repeat expansion in the intron 1 of the C9ORF72 gene can cause amyotrophic lateral sclerosis (ALS) and frontal temporal dementia (FTD). Here the authors use single molecule imaging to show nuclear export and translation of circular repeat-containing C9ORF72 intronic RNA.Shaopeng WangMalgorzata J. LatalloZhe ZhangBo HuangDmitriy G. BobrovnikovDaoyuan DongNathan M. LivingstonWilson TjoengLindsey R. HayesJeffrey D. RothsteinLyle W. OstrowBin WuShuying SunNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Shaopeng Wang Malgorzata J. Latallo Zhe Zhang Bo Huang Dmitriy G. Bobrovnikov Daoyuan Dong Nathan M. Livingston Wilson Tjoeng Lindsey R. Hayes Jeffrey D. Rothstein Lyle W. Ostrow Bin Wu Shuying Sun Nuclear export and translation of circular repeat-containing intronic RNA in C9ORF72-ALS/FTD
description	Hexanucleotide repeat expansion in the intron 1 of the C9ORF72 gene can cause amyotrophic lateral sclerosis (ALS) and frontal temporal dementia (FTD). Here the authors use single molecule imaging to show nuclear export and translation of circular repeat-containing C9ORF72 intronic RNA.
format	article
author	Shaopeng Wang Malgorzata J. Latallo Zhe Zhang Bo Huang Dmitriy G. Bobrovnikov Daoyuan Dong Nathan M. Livingston Wilson Tjoeng Lindsey R. Hayes Jeffrey D. Rothstein Lyle W. Ostrow Bin Wu Shuying Sun
author_facet	Shaopeng Wang Malgorzata J. Latallo Zhe Zhang Bo Huang Dmitriy G. Bobrovnikov Daoyuan Dong Nathan M. Livingston Wilson Tjoeng Lindsey R. Hayes Jeffrey D. Rothstein Lyle W. Ostrow Bin Wu Shuying Sun
author_sort	Shaopeng Wang
title	Nuclear export and translation of circular repeat-containing intronic RNA in C9ORF72-ALS/FTD
title_short	Nuclear export and translation of circular repeat-containing intronic RNA in C9ORF72-ALS/FTD
title_full	Nuclear export and translation of circular repeat-containing intronic RNA in C9ORF72-ALS/FTD
title_fullStr	Nuclear export and translation of circular repeat-containing intronic RNA in C9ORF72-ALS/FTD
title_full_unstemmed	Nuclear export and translation of circular repeat-containing intronic RNA in C9ORF72-ALS/FTD
title_sort	nuclear export and translation of circular repeat-containing intronic rna in c9orf72-als/ftd
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/fa693cbc636a4db9b4b2a4b8bdc7fe5c
work_keys_str_mv	AT shaopengwang nuclearexportandtranslationofcircularrepeatcontainingintronicrnainc9orf72alsftd AT malgorzatajlatallo nuclearexportandtranslationofcircularrepeatcontainingintronicrnainc9orf72alsftd AT zhezhang nuclearexportandtranslationofcircularrepeatcontainingintronicrnainc9orf72alsftd AT bohuang nuclearexportandtranslationofcircularrepeatcontainingintronicrnainc9orf72alsftd AT dmitriygbobrovnikov nuclearexportandtranslationofcircularrepeatcontainingintronicrnainc9orf72alsftd AT daoyuandong nuclearexportandtranslationofcircularrepeatcontainingintronicrnainc9orf72alsftd AT nathanmlivingston nuclearexportandtranslationofcircularrepeatcontainingintronicrnainc9orf72alsftd AT wilsontjoeng nuclearexportandtranslationofcircularrepeatcontainingintronicrnainc9orf72alsftd AT lindseyrhayes nuclearexportandtranslationofcircularrepeatcontainingintronicrnainc9orf72alsftd AT jeffreydrothstein nuclearexportandtranslationofcircularrepeatcontainingintronicrnainc9orf72alsftd AT lylewostrow nuclearexportandtranslationofcircularrepeatcontainingintronicrnainc9orf72alsftd AT binwu nuclearexportandtranslationofcircularrepeatcontainingintronicrnainc9orf72alsftd AT shuyingsun nuclearexportandtranslationofcircularrepeatcontainingintronicrnainc9orf72alsftd
_version_	1718383970734833664

Nuclear export and translation of circular repeat-containing intronic RNA in C9ORF72-ALS/FTD

Ejemplares similares