Nuclear export and translation of circular repeat-containing intronic RNA in C9ORF72-ALS/FTD

Nuclear export and translation of circular repeat-containing intronic RNA in C9ORF72-ALS/FTD

Hexanucleotide repeat expansion in the intron 1 of the C9ORF72 gene can cause amyotrophic lateral sclerosis (ALS) and frontal temporal dementia (FTD). Here the authors use single molecule imaging to show nuclear export and translation of circular repeat-containing C9ORF72 intronic RNA.

Saved in:
Bibliographic Details
Main Authors: Shaopeng Wang, Malgorzata J. Latallo, Zhe Zhang, Bo Huang, Dmitriy G. Bobrovnikov, Daoyuan Dong, Nathan M. Livingston, Wilson Tjoeng, Lindsey R. Hayes, Jeffrey D. Rothstein, Lyle W. Ostrow, Bin Wu, Shuying Sun
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
Science
Q
Online Access:https://doaj.org/article/fa693cbc636a4db9b4b2a4b8bdc7fe5c
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items