Glucocorticosteroids differentially regulate MMP-9 and neutrophil elastase in COPD.

Glucocorticosteroids differentially regulate MMP-9 and neutrophil elastase in COPD.

<h4>Background</h4>Chronic Obstructive Pulmonary Disease (COPD) is currently the fifth leading cause of death worldwide. Neutrophilic inflammation is prominent, worsened during infective exacerbations and is refractory to glucocorticosteroids (GCs). Deregulated neutrophilic inflammation...

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Autores principales: Ross Vlahos, Peter A B Wark, Gary P Anderson, Steven Bozinovski
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
Materias:
Medicine
R
Science
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Acceso en línea:https://doaj.org/article/fa6ada3c0271488baac4d36c250aaa40
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