Multiple concurrent and convergent stages of genome reduction in bacterial symbionts across a stink bug family

Abstract Nutritional symbioses between bacteria and insects are prevalent and diverse, allowing insects to expand their feeding strategies and niches. A common consequence of long-term associations is a considerable reduction in symbiont genome size likely influenced by the radical shift in selectiv...

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Autores principales:	Alejandro Otero-Bravo, Zakee L. Sabree
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/fa6c96165bea434eb2dba5de2b48642c
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spelling	oai:doaj.org-article:fa6c96165bea434eb2dba5de2b48642c2021-12-02T18:15:33ZMultiple concurrent and convergent stages of genome reduction in bacterial symbionts across a stink bug family10.1038/s41598-021-86574-82045-2322https://doaj.org/article/fa6c96165bea434eb2dba5de2b48642c2021-04-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-86574-8https://doaj.org/toc/2045-2322Abstract Nutritional symbioses between bacteria and insects are prevalent and diverse, allowing insects to expand their feeding strategies and niches. A common consequence of long-term associations is a considerable reduction in symbiont genome size likely influenced by the radical shift in selective pressures as a result of the less variable environment within the host. While several of these cases can be found across distinct insect species, most examples provide a limited view of a single or few stages of the process of genome reduction. Stink bugs (Pentatomidae) contain inherited gamma-proteobacterial symbionts in a modified organ in their midgut and are an example of a long-term nutritional symbiosis, but multiple cases of new symbiont acquisition throughout the history of the family have been described. We sequenced the genomes of 11 symbionts of stink bugs with sizes that ranged from equal to those of their free-living relatives to less than 20%. Comparative genomics of these and previously sequenced symbionts revealed initial stages of genome reduction including an initial pseudogenization before genome reduction, followed by multiple stages of progressive degeneration of existing metabolic pathways likely to impact host interactions such as cell wall component biosynthesis. Amino acid biosynthesis pathways were retained in a similar manner as in other nutritional symbionts. Stink bug symbionts display convergent genome reduction events showing progressive changes from a free-living bacterium to a host-dependent symbiont. This system can therefore be used to study convergent genome evolution of symbiosis at a scale not previously available.Alejandro Otero-BravoZakee L. SabreeNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Alejandro Otero-Bravo Zakee L. Sabree Multiple concurrent and convergent stages of genome reduction in bacterial symbionts across a stink bug family
description	Abstract Nutritional symbioses between bacteria and insects are prevalent and diverse, allowing insects to expand their feeding strategies and niches. A common consequence of long-term associations is a considerable reduction in symbiont genome size likely influenced by the radical shift in selective pressures as a result of the less variable environment within the host. While several of these cases can be found across distinct insect species, most examples provide a limited view of a single or few stages of the process of genome reduction. Stink bugs (Pentatomidae) contain inherited gamma-proteobacterial symbionts in a modified organ in their midgut and are an example of a long-term nutritional symbiosis, but multiple cases of new symbiont acquisition throughout the history of the family have been described. We sequenced the genomes of 11 symbionts of stink bugs with sizes that ranged from equal to those of their free-living relatives to less than 20%. Comparative genomics of these and previously sequenced symbionts revealed initial stages of genome reduction including an initial pseudogenization before genome reduction, followed by multiple stages of progressive degeneration of existing metabolic pathways likely to impact host interactions such as cell wall component biosynthesis. Amino acid biosynthesis pathways were retained in a similar manner as in other nutritional symbionts. Stink bug symbionts display convergent genome reduction events showing progressive changes from a free-living bacterium to a host-dependent symbiont. This system can therefore be used to study convergent genome evolution of symbiosis at a scale not previously available.
format	article
author	Alejandro Otero-Bravo Zakee L. Sabree
author_facet	Alejandro Otero-Bravo Zakee L. Sabree
author_sort	Alejandro Otero-Bravo
title	Multiple concurrent and convergent stages of genome reduction in bacterial symbionts across a stink bug family
title_short	Multiple concurrent and convergent stages of genome reduction in bacterial symbionts across a stink bug family
title_full	Multiple concurrent and convergent stages of genome reduction in bacterial symbionts across a stink bug family
title_fullStr	Multiple concurrent and convergent stages of genome reduction in bacterial symbionts across a stink bug family
title_full_unstemmed	Multiple concurrent and convergent stages of genome reduction in bacterial symbionts across a stink bug family
title_sort	multiple concurrent and convergent stages of genome reduction in bacterial symbionts across a stink bug family
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/fa6c96165bea434eb2dba5de2b48642c
work_keys_str_mv	AT alejandrooterobravo multipleconcurrentandconvergentstagesofgenomereductioninbacterialsymbiontsacrossastinkbugfamily AT zakeelsabree multipleconcurrentandconvergentstagesofgenomereductioninbacterialsymbiontsacrossastinkbugfamily
_version_	1718378371890544640

Multiple concurrent and convergent stages of genome reduction in bacterial symbionts across a stink bug family

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