Epigraph hemagglutinin vaccine induces broad cross-reactive immunity against swine H3 influenza virus

A range of Influenza vaccines have been linked to induction of adaptive immunity in a number of animal models. Here, the authors utilize a computational design strategy and produce a swine H3 influenza vaccine which shows enhanced efficacy in both murine and porcine infectious disease models.

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Autores principales:	Brianna L. Bullard, Brigette N. Corder, Jennifer DeBeauchamp, Adam Rubrum, Bette Korber, Richard J. Webby, Eric A. Weaver
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/fa72364cc6b54183af6c5e1482456e79
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spelling	oai:doaj.org-article:fa72364cc6b54183af6c5e1482456e792021-12-02T11:02:37ZEpigraph hemagglutinin vaccine induces broad cross-reactive immunity against swine H3 influenza virus10.1038/s41467-021-21508-62041-1723https://doaj.org/article/fa72364cc6b54183af6c5e1482456e792021-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-21508-6https://doaj.org/toc/2041-1723A range of Influenza vaccines have been linked to induction of adaptive immunity in a number of animal models. Here, the authors utilize a computational design strategy and produce a swine H3 influenza vaccine which shows enhanced efficacy in both murine and porcine infectious disease models.Brianna L. BullardBrigette N. CorderJennifer DeBeauchampAdam RubrumBette KorberRichard J. WebbyEric A. WeaverNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Brianna L. Bullard Brigette N. Corder Jennifer DeBeauchamp Adam Rubrum Bette Korber Richard J. Webby Eric A. Weaver Epigraph hemagglutinin vaccine induces broad cross-reactive immunity against swine H3 influenza virus
description	A range of Influenza vaccines have been linked to induction of adaptive immunity in a number of animal models. Here, the authors utilize a computational design strategy and produce a swine H3 influenza vaccine which shows enhanced efficacy in both murine and porcine infectious disease models.
format	article
author	Brianna L. Bullard Brigette N. Corder Jennifer DeBeauchamp Adam Rubrum Bette Korber Richard J. Webby Eric A. Weaver
author_facet	Brianna L. Bullard Brigette N. Corder Jennifer DeBeauchamp Adam Rubrum Bette Korber Richard J. Webby Eric A. Weaver
author_sort	Brianna L. Bullard
title	Epigraph hemagglutinin vaccine induces broad cross-reactive immunity against swine H3 influenza virus
title_short	Epigraph hemagglutinin vaccine induces broad cross-reactive immunity against swine H3 influenza virus
title_full	Epigraph hemagglutinin vaccine induces broad cross-reactive immunity against swine H3 influenza virus
title_fullStr	Epigraph hemagglutinin vaccine induces broad cross-reactive immunity against swine H3 influenza virus
title_full_unstemmed	Epigraph hemagglutinin vaccine induces broad cross-reactive immunity against swine H3 influenza virus
title_sort	epigraph hemagglutinin vaccine induces broad cross-reactive immunity against swine h3 influenza virus
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/fa72364cc6b54183af6c5e1482456e79
work_keys_str_mv	AT briannalbullard epigraphhemagglutininvaccineinducesbroadcrossreactiveimmunityagainstswineh3influenzavirus AT brigettencorder epigraphhemagglutininvaccineinducesbroadcrossreactiveimmunityagainstswineh3influenzavirus AT jenniferdebeauchamp epigraphhemagglutininvaccineinducesbroadcrossreactiveimmunityagainstswineh3influenzavirus AT adamrubrum epigraphhemagglutininvaccineinducesbroadcrossreactiveimmunityagainstswineh3influenzavirus AT bettekorber epigraphhemagglutininvaccineinducesbroadcrossreactiveimmunityagainstswineh3influenzavirus AT richardjwebby epigraphhemagglutininvaccineinducesbroadcrossreactiveimmunityagainstswineh3influenzavirus AT ericaweaver epigraphhemagglutininvaccineinducesbroadcrossreactiveimmunityagainstswineh3influenzavirus
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Epigraph hemagglutinin vaccine induces broad cross-reactive immunity against swine H3 influenza virus

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