Monoarticular Crystal Arthropathy of the Knee: Tophaceous Gout

Tophaceous gout is a crystal arthropathy and a disorder of purine metabolism characterized by monosodium urate crystal deposition. A case of tophaceous gout of the knee joint in a 30-year-old female is reported, and the imaging appearances on high-resolution ultrasonography are described. The patien...

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Autor principal:	Ravikanth Reddy
Formato:	article
Lenguaje:	EN
Publicado:	Karger Publishers 2021
Materias:	tophaceous gout female patient high-resolution ultrasonography knee joint monosodium urate crystals Medicine R
Acceso en línea:	https://doaj.org/article/fa7de4b6aad541078197d0dbc768b2b2
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spelling	oai:doaj.org-article:fa7de4b6aad541078197d0dbc768b2b22021-11-11T10:40:46ZMonoarticular Crystal Arthropathy of the Knee: Tophaceous Gout2571-726X10.1159/000519571https://doaj.org/article/fa7de4b6aad541078197d0dbc768b2b22021-10-01T00:00:00Zhttps://www.karger.com/Article/FullText/519571https://doaj.org/toc/2571-726XTophaceous gout is a crystal arthropathy and a disorder of purine metabolism characterized by monosodium urate crystal deposition. A case of tophaceous gout of the knee joint in a 30-year-old female is reported, and the imaging appearances on high-resolution ultrasonography are described. The patient presented with complaints of insidious onset painless swelling of the left knee joint with limitation of range of movement for 1 week. The aspirated joint fluid demonstrated needle-like monosodium urate crystals showing strong negative birefringence consistent with a diagnosis of tophaceous gout. Targeted urate-lowering treatment included oral nonsteroidal anti-inflammatory drugs and oral colchicine. Prophylactic treatment for gout flare-ups included initiation of allopurinol at 300 mg/day along with modification of the dietary regimen including limited consumption of red meat and increased consumption of low-fat dairy products. Symptomatic improvement with reduced pain and swelling of the knee joint was noted at 10 days after treatment. Subsequently, at 3-month follow-up, the patient was disease free with no signs of recurrence and serum uric acid levels at 3.7 mg/dL. In spite of a wide range of therapeutic options available for the management of tophaceous gout, suboptimal management of gout is prevalent till date in both developing and developed nations across the world.Ravikanth ReddyKarger Publishersarticletophaceous goutfemale patienthigh-resolution ultrasonographyknee jointmonosodium urate crystalsMedicineRENDubai Medical Journal, Pp 1-5 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	tophaceous gout female patient high-resolution ultrasonography knee joint monosodium urate crystals Medicine R
spellingShingle	tophaceous gout female patient high-resolution ultrasonography knee joint monosodium urate crystals Medicine R Ravikanth Reddy Monoarticular Crystal Arthropathy of the Knee: Tophaceous Gout
description	Tophaceous gout is a crystal arthropathy and a disorder of purine metabolism characterized by monosodium urate crystal deposition. A case of tophaceous gout of the knee joint in a 30-year-old female is reported, and the imaging appearances on high-resolution ultrasonography are described. The patient presented with complaints of insidious onset painless swelling of the left knee joint with limitation of range of movement for 1 week. The aspirated joint fluid demonstrated needle-like monosodium urate crystals showing strong negative birefringence consistent with a diagnosis of tophaceous gout. Targeted urate-lowering treatment included oral nonsteroidal anti-inflammatory drugs and oral colchicine. Prophylactic treatment for gout flare-ups included initiation of allopurinol at 300 mg/day along with modification of the dietary regimen including limited consumption of red meat and increased consumption of low-fat dairy products. Symptomatic improvement with reduced pain and swelling of the knee joint was noted at 10 days after treatment. Subsequently, at 3-month follow-up, the patient was disease free with no signs of recurrence and serum uric acid levels at 3.7 mg/dL. In spite of a wide range of therapeutic options available for the management of tophaceous gout, suboptimal management of gout is prevalent till date in both developing and developed nations across the world.
format	article
author	Ravikanth Reddy
author_facet	Ravikanth Reddy
author_sort	Ravikanth Reddy
title	Monoarticular Crystal Arthropathy of the Knee: Tophaceous Gout
title_short	Monoarticular Crystal Arthropathy of the Knee: Tophaceous Gout
title_full	Monoarticular Crystal Arthropathy of the Knee: Tophaceous Gout
title_fullStr	Monoarticular Crystal Arthropathy of the Knee: Tophaceous Gout
title_full_unstemmed	Monoarticular Crystal Arthropathy of the Knee: Tophaceous Gout
title_sort	monoarticular crystal arthropathy of the knee: tophaceous gout
publisher	Karger Publishers
publishDate	2021
url	https://doaj.org/article/fa7de4b6aad541078197d0dbc768b2b2
work_keys_str_mv	AT ravikanthreddy monoarticularcrystalarthropathyofthekneetophaceousgout
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Monoarticular Crystal Arthropathy of the Knee: Tophaceous Gout

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