Pleiotropic Effects of the P5-Type ATPase SpfA on Stress Response Networks Contribute to Virulence in the Pathogenic Mold Aspergillus fumigatus
The fungal UPR is an adaptive signaling pathway in the ER that buffers fluctuations in ER stress but also serves as a virulence regulatory hub in species of pathogenic fungi that rely on secretory pathway homeostasis for pathogenicity. This study demonstrates that the gene encoding the ER-localize...
Guardado en:
Autores principales: | José P. Guirao-Abad, Martin Weichert, Ginés Luengo-Gil, Sarah Sze Wah Wong, Vishukumar Aimanianda, Christina Grisham, Nikita Malev, Shivani Reddy, Laura Woollett, David S. Askew |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
American Society for Microbiology
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/fa945191fa4942a0a1c0c0808abce8b6 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Functional Coupling between the Unfolded Protein Response and Endoplasmic Reticulum/Golgi Ca<sup>2+</sup>-ATPases Promotes Stress Tolerance, Cell Wall Biosynthesis, and Virulence of <named-content content-type="genus-species">Aspergillus fumigatus</named-content>
por: Martin Weichert, et al.
Publicado: (2020) -
A Human IRE1 Inhibitor Blocks the Unfolded Protein Response in the Pathogenic Fungus <named-content content-type="genus-species">Aspergillus fumigatus</named-content> and Suggests Noncanonical Functions within the Pathway
por: José P. Guirao-Abad, et al.
Publicado: (2020) -
Functional Genomic and Biochemical Analysis Reveals Pleiotropic Effect of Congo Red on Aspergillus fumigatus
por: Zhonghua Liu, et al.
Publicado: (2021) -
HacA-independent functions of the ER stress sensor IreA synergize with the canonical UPR to influence virulence traits in Aspergillus fumigatus.
por: Xizhi Feng, et al.
Publicado: (2011) -
<named-content content-type="genus-species">Aspergillus fumigatus</named-content> Transcription Factors Involved in the Caspofungin Paradoxical Effect
por: Clara Valero, et al.
Publicado: (2020)