High Dimensional Immune Profiling Reveals Different Response Patterns in Active and Latent Tuberculosis Following Stimulation With Mycobacterial Glycolipids

High Dimensional Immune Profiling Reveals Different Response Patterns in Active and Latent Tuberculosis Following Stimulation With Mycobacterial Glycolipids

Upon infection with Mycobacterium tuberculosis (Mtb) the host immune response might clear the bacteria, control its growth leading to latent tuberculosis (LTB), or fail to control its growth resulting in active TB (ATB). There is however no clear understanding of the features underlying a more or le...

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Bibliographic Details
Main Authors: Carolina S. Silva, Christopher Sundling, Elin Folkesson, Gabrielle Fröberg, Claudia Nobrega, João Canto-Gomes, Benedict J. Chambers, Tadepally Lakshmikanth, Petter Brodin, Judith Bruchfeld, Jérôme Nigou, Margarida Correia-Neves, Gunilla Källenius
Format: article
Language:EN
Published: Frontiers Media S.A. 2021
Subjects:
tuberculosis
mycobacterial glycolipids
active tuberculosis (ATB)
latent tuberculosis (LTB)
hyporesponsiveness
lipoarabinomannan (LAM)
Immunologic diseases. Allergy
RC581-607
Online Access:https://doaj.org/article/fa96c632e81d4eb29b1785a92977feef
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https://doaj.org/article/fa96c632e81d4eb29b1785a92977feef

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