Drebrin controls scar formation and astrocyte reactivity upon traumatic brain injury by regulating membrane trafficking

Drebrin controls scar formation and astrocyte reactivity upon traumatic brain injury by regulating membrane trafficking

Reactive astrocytes control tissue damage following traumatic brain injury. Here the authors show that Drebrin (DBN) regulates scar formation and astrocyte reactivity in mice. Astrocytic DBN plays its neuroprotective role through the mediation of membrane trafficking.

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Auteurs principaux: Juliane Schiweck, Kai Murk, Julia Ledderose, Agnieszka Münster-Wandowski, Marta Ornaghi, Imre Vida, Britta J. Eickholt
Format: article
Langue:EN
Publié: Nature Portfolio 2021
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Accès en ligne:https://doaj.org/article/faa00833f92f403a9cfda9770b33cec8
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spelling oai:doaj.org-article:faa00833f92f403a9cfda9770b33cec82021-12-02T13:33:01ZDrebrin controls scar formation and astrocyte reactivity upon traumatic brain injury by regulating membrane trafficking10.1038/s41467-021-21662-x2041-1723https://doaj.org/article/faa00833f92f403a9cfda9770b33cec82021-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-21662-xhttps://doaj.org/toc/2041-1723Reactive astrocytes control tissue damage following traumatic brain injury. Here the authors show that Drebrin (DBN) regulates scar formation and astrocyte reactivity in mice. Astrocytic DBN plays its neuroprotective role through the mediation of membrane trafficking.Juliane SchiweckKai MurkJulia LedderoseAgnieszka Münster-WandowskiMarta OrnaghiImre VidaBritta J. EickholtNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Juliane Schiweck
Kai Murk
Julia Ledderose
Agnieszka Münster-Wandowski
Marta Ornaghi
Imre Vida
Britta J. Eickholt
Drebrin controls scar formation and astrocyte reactivity upon traumatic brain injury by regulating membrane trafficking
description Reactive astrocytes control tissue damage following traumatic brain injury. Here the authors show that Drebrin (DBN) regulates scar formation and astrocyte reactivity in mice. Astrocytic DBN plays its neuroprotective role through the mediation of membrane trafficking.
format article
author Juliane Schiweck
Kai Murk
Julia Ledderose
Agnieszka Münster-Wandowski
Marta Ornaghi
Imre Vida
Britta J. Eickholt
author_facet Juliane Schiweck
Kai Murk
Julia Ledderose
Agnieszka Münster-Wandowski
Marta Ornaghi
Imre Vida
Britta J. Eickholt
author_sort Juliane Schiweck
title Drebrin controls scar formation and astrocyte reactivity upon traumatic brain injury by regulating membrane trafficking
title_short Drebrin controls scar formation and astrocyte reactivity upon traumatic brain injury by regulating membrane trafficking
title_full Drebrin controls scar formation and astrocyte reactivity upon traumatic brain injury by regulating membrane trafficking
title_fullStr Drebrin controls scar formation and astrocyte reactivity upon traumatic brain injury by regulating membrane trafficking
title_full_unstemmed Drebrin controls scar formation and astrocyte reactivity upon traumatic brain injury by regulating membrane trafficking
title_sort drebrin controls scar formation and astrocyte reactivity upon traumatic brain injury by regulating membrane trafficking
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/faa00833f92f403a9cfda9770b33cec8
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AT julialedderose drebrincontrolsscarformationandastrocytereactivityupontraumaticbraininjurybyregulatingmembranetrafficking
AT agnieszkamunsterwandowski drebrincontrolsscarformationandastrocytereactivityupontraumaticbraininjurybyregulatingmembranetrafficking
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AT imrevida drebrincontrolsscarformationandastrocytereactivityupontraumaticbraininjurybyregulatingmembranetrafficking
AT brittajeickholt drebrincontrolsscarformationandastrocytereactivityupontraumaticbraininjurybyregulatingmembranetrafficking
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