Drebrin controls scar formation and astrocyte reactivity upon traumatic brain injury by regulating membrane trafficking

Reactive astrocytes control tissue damage following traumatic brain injury. Here the authors show that Drebrin (DBN) regulates scar formation and astrocyte reactivity in mice. Astrocytic DBN plays its neuroprotective role through the mediation of membrane trafficking.

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Autores principales:	Juliane Schiweck, Kai Murk, Julia Ledderose, Agnieszka Münster-Wandowski, Marta Ornaghi, Imre Vida, Britta J. Eickholt
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/faa00833f92f403a9cfda9770b33cec8
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spelling	oai:doaj.org-article:faa00833f92f403a9cfda9770b33cec82021-12-02T13:33:01ZDrebrin controls scar formation and astrocyte reactivity upon traumatic brain injury by regulating membrane trafficking10.1038/s41467-021-21662-x2041-1723https://doaj.org/article/faa00833f92f403a9cfda9770b33cec82021-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-21662-xhttps://doaj.org/toc/2041-1723Reactive astrocytes control tissue damage following traumatic brain injury. Here the authors show that Drebrin (DBN) regulates scar formation and astrocyte reactivity in mice. Astrocytic DBN plays its neuroprotective role through the mediation of membrane trafficking.Juliane SchiweckKai MurkJulia LedderoseAgnieszka Münster-WandowskiMarta OrnaghiImre VidaBritta J. EickholtNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Juliane Schiweck Kai Murk Julia Ledderose Agnieszka Münster-Wandowski Marta Ornaghi Imre Vida Britta J. Eickholt Drebrin controls scar formation and astrocyte reactivity upon traumatic brain injury by regulating membrane trafficking
description	Reactive astrocytes control tissue damage following traumatic brain injury. Here the authors show that Drebrin (DBN) regulates scar formation and astrocyte reactivity in mice. Astrocytic DBN plays its neuroprotective role through the mediation of membrane trafficking.
format	article
author	Juliane Schiweck Kai Murk Julia Ledderose Agnieszka Münster-Wandowski Marta Ornaghi Imre Vida Britta J. Eickholt
author_facet	Juliane Schiweck Kai Murk Julia Ledderose Agnieszka Münster-Wandowski Marta Ornaghi Imre Vida Britta J. Eickholt
author_sort	Juliane Schiweck
title	Drebrin controls scar formation and astrocyte reactivity upon traumatic brain injury by regulating membrane trafficking
title_short	Drebrin controls scar formation and astrocyte reactivity upon traumatic brain injury by regulating membrane trafficking
title_full	Drebrin controls scar formation and astrocyte reactivity upon traumatic brain injury by regulating membrane trafficking
title_fullStr	Drebrin controls scar formation and astrocyte reactivity upon traumatic brain injury by regulating membrane trafficking
title_full_unstemmed	Drebrin controls scar formation and astrocyte reactivity upon traumatic brain injury by regulating membrane trafficking
title_sort	drebrin controls scar formation and astrocyte reactivity upon traumatic brain injury by regulating membrane trafficking
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/faa00833f92f403a9cfda9770b33cec8
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Drebrin controls scar formation and astrocyte reactivity upon traumatic brain injury by regulating membrane trafficking

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