Drebrin controls scar formation and astrocyte reactivity upon traumatic brain injury by regulating membrane trafficking

Reactive astrocytes control tissue damage following traumatic brain injury. Here the authors show that Drebrin (DBN) regulates scar formation and astrocyte reactivity in mice. Astrocytic DBN plays its neuroprotective role through the mediation of membrane trafficking.

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Autores principales: Juliane Schiweck, Kai Murk, Julia Ledderose, Agnieszka Münster-Wandowski, Marta Ornaghi, Imre Vida, Britta J. Eickholt
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/faa00833f92f403a9cfda9770b33cec8
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