AIP limits neurotransmitter release by inhibiting calcium bursts from the ryanodine receptor

In this work the authors show that AIP (aryl hydrocarbon receptor-interacting protein), a gene frequently mutated in association with pituitary tumors, regulates neurotransmitter release by inhibiting calcium release from ryanodine receptors.

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Auteurs principaux: Bojun Chen, Ping Liu, Edward J. Hujber, Yan Li, Erik M. Jorgensen, Zhao-Wen Wang
Format: article
Langue:EN
Publié: Nature Portfolio 2017
Sujets:
Q
Accès en ligne:https://doaj.org/article/faa053a3d2284cf6a3644a5c44e22d47
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Résumé:In this work the authors show that AIP (aryl hydrocarbon receptor-interacting protein), a gene frequently mutated in association with pituitary tumors, regulates neurotransmitter release by inhibiting calcium release from ryanodine receptors.